Table 3.

Summary of the disease-oriented treatment of patients with WHIM syndrome

RecommendedOptional/experimental
Infections
Hypogammaglobulinemia 
Immunoglobulin replacement treatment  
IV: 400 mg/kg monthly 
SC: 100 mg/kg weekly 
Neutropenia None G-CSF (1-2 μg/kg daily) 
Warts Imiquimod (topical) Plerixafor (0.01-0.02 mg/kg SC twice daily) 
Other dermatological therapies (ie, laser therapy and cryotherapy) 
RecommendedOptional/experimental
Infections
Hypogammaglobulinemia 
Immunoglobulin replacement treatment  
IV: 400 mg/kg monthly 
SC: 100 mg/kg weekly 
Neutropenia None G-CSF (1-2 μg/kg daily) 
Warts Imiquimod (topical) Plerixafor (0.01-0.02 mg/kg SC twice daily) 
Other dermatological therapies (ie, laser therapy and cryotherapy) 

SC, subcutaneously.

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