CBC of WT and Tr4+/− adult mice
| Blood count parameter . | Tr4 WT . | Tr4+/− . |
|---|---|---|
| 6-to 8-wk-old mice | ||
| WBC (×103 cells/μL) | 6.68 ± 0.49 | 5.78 ± 0.48 |
| RBC (×106 cells/μL) | 8.28 ± 0.56 | 6.03 ± 0.52* |
| PLT (×103 cells/μL) | 313.4 ± 33.46 | 343 ± 25.09 |
| Hb (g/dL) | 12.8 ± 0.48 | 10.32 ± 0.40* |
| HCT (%) | 46.68 ± 1.35 | 30.67 ± 1.75* |
| MCH (pg) | 14.06 ± 0.61 | 17.8 ± 2.90 |
| MPV (fL) | 5.86 ± 0.09 | 5.92 ± 0.13 |
| MCV (fL) | 51.12 ± 1.32 | 57.08 ± 2.06 |
| MCHC (pg) | 28.83 ± 1.35 | 34.16 ± 2.76 |
| RDW (%) | 26.5 ± 2.45 | 28.86 ± 0.83 |
| Neutrophil (%) | 8.76 ± 1.94 | 10.61 ± 2.06 |
| Lymphocyte (%) | 83.33 ± 34 | 79.62 ± 2.30 |
| Monocyte (%) | 6.83 ± 0.62 | 6.96 ± 0.86 |
| Eosinophil (%) | 1.27 ± 0.17 | 2.35 ± 0.46 |
| Basophil (%) | 0.20 ± 0.07 | 0.11 ± 0.55 |
| 6-mo-old mice | ||
| RBC (×106 cells/μL) | 9.32 ± 0.07 | 6.3 ± 0.44* |
| Hb (g/dL) | 15.75 ± 0.75 | 10.47 ± 1.45* |
| HCT (%) | 47 ± 2 | 31 ± 7.21* |
| Blood count parameter . | Tr4 WT . | Tr4+/− . |
|---|---|---|
| 6-to 8-wk-old mice | ||
| WBC (×103 cells/μL) | 6.68 ± 0.49 | 5.78 ± 0.48 |
| RBC (×106 cells/μL) | 8.28 ± 0.56 | 6.03 ± 0.52* |
| PLT (×103 cells/μL) | 313.4 ± 33.46 | 343 ± 25.09 |
| Hb (g/dL) | 12.8 ± 0.48 | 10.32 ± 0.40* |
| HCT (%) | 46.68 ± 1.35 | 30.67 ± 1.75* |
| MCH (pg) | 14.06 ± 0.61 | 17.8 ± 2.90 |
| MPV (fL) | 5.86 ± 0.09 | 5.92 ± 0.13 |
| MCV (fL) | 51.12 ± 1.32 | 57.08 ± 2.06 |
| MCHC (pg) | 28.83 ± 1.35 | 34.16 ± 2.76 |
| RDW (%) | 26.5 ± 2.45 | 28.86 ± 0.83 |
| Neutrophil (%) | 8.76 ± 1.94 | 10.61 ± 2.06 |
| Lymphocyte (%) | 83.33 ± 34 | 79.62 ± 2.30 |
| Monocyte (%) | 6.83 ± 0.62 | 6.96 ± 0.86 |
| Eosinophil (%) | 1.27 ± 0.17 | 2.35 ± 0.46 |
| Basophil (%) | 0.20 ± 0.07 | 0.11 ± 0.55 |
| 6-mo-old mice | ||
| RBC (×106 cells/μL) | 9.32 ± 0.07 | 6.3 ± 0.44* |
| Hb (g/dL) | 15.75 ± 0.75 | 10.47 ± 1.45* |
| HCT (%) | 47 ± 2 | 31 ± 7.21* |
Peripheral blood samples were taken from 6- to 8-week-old adult mice and blood count parameters were quantified.
MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MPV, mean platelet volume; PLT, platelet; RDW, red blood cell distribution width; WBC, white blood cell.
P < .05 as determined by Student t test comparing Tr4+/− to WT.