Characteristics of peripheral blood and RBC sphingolipid concentration 6 weeks after bone marrow transplantation
| Genotype . | HNF1A+/+ → HNF1A+/+, n = 6 . | HNF1A−/− → HNF1A+/+, n = 5 . |
|---|---|---|
| Blood parameters | ||
| HCT, % | 48.2 ± 3.2 | 45.6 ± 2.9 |
| HGB, g/dL | 16.7 ± 1.1 | 15.5 ± 1.4 |
| RBC, (×106)/µL blood | 11.2 ± 0.8 | 10.4 ± 0.3 |
| MCV, µm3 | 50.0 ± 1.4 | 52.4 ± 0.7 |
| MCH, pg | 15.1 ± 0.3 | 14.9 ± 0.6 |
| MCHC, g/dL | 30.2 ± 0.3 | 28.5 ± 1.3 |
| RDW, % | 14.2 ± 1.1 | 13.6 ± 0.2 |
| Sphingolipids, nM | ||
| Sphingosine | 4 321 ± 436 | 4 614 ± 236 |
| C16-ceramide | 539 ± 108 | 510 ± 77 |
| Sphingomyelin | 241 000 ± 12 959 | 230 560 ± 9 788 |
| Genotype . | HNF1A+/+ → HNF1A+/+, n = 6 . | HNF1A−/− → HNF1A+/+, n = 5 . |
|---|---|---|
| Blood parameters | ||
| HCT, % | 48.2 ± 3.2 | 45.6 ± 2.9 |
| HGB, g/dL | 16.7 ± 1.1 | 15.5 ± 1.4 |
| RBC, (×106)/µL blood | 11.2 ± 0.8 | 10.4 ± 0.3 |
| MCV, µm3 | 50.0 ± 1.4 | 52.4 ± 0.7 |
| MCH, pg | 15.1 ± 0.3 | 14.9 ± 0.6 |
| MCHC, g/dL | 30.2 ± 0.3 | 28.5 ± 1.3 |
| RDW, % | 14.2 ± 1.1 | 13.6 ± 0.2 |
| Sphingolipids, nM | ||
| Sphingosine | 4 321 ± 436 | 4 614 ± 236 |
| C16-ceramide | 539 ± 108 | 510 ± 77 |
| Sphingomyelin | 241 000 ± 12 959 | 230 560 ± 9 788 |
Data are presented as mean ± SEM and were analyzed for significant differences with a Student t test.