Table 2.

Univariate analysis for baseline prognostic factors of survival

Prognostic factorPFSOS
HR (95% CI)PHR (95% CI)P
Male 1.3 (0.6-2.7) .53 0.7 (0.2-2.3) .60 
Age ≥50 y 1.8 (0.6-5.6) .18 2.2 (0.4-11.4) .23 
Mixed cellularity 0.8 (0.3-2.2) .68 1.1 (0.2-4.8) .92 
Presence of B symptoms 2.9 (1.3-6.7) .0035 4.6 (1.3-15.6) .006 
≥4 Involved sites 2.7 (0.7- 9.5) .028 4.7 (0.7-31.5) .006 
Bulk mediastinum (M/T ≥ 0.35) 0.9-5.7 .026 2.3 (0.6-8.9) .13 
TMTV >147 cm3 5.2 (1.8-14.7) <.0001 7.2 (1.6-33.4) .0001 
U EORTC 5.7 (2.7-12.3) .0013 NR .0039 
U GHSG 2.8 (1.3-6.3) .046 5.3 (1.6-17.6) .075 
U NCCN 3.6 (1.7-7.9) .011 6.7 (2.1-21.6) .034 
Positive iPET2 (DS 4-5) 12 (2.3-63.7) <.0001 13.2 (1.4-128.3) <.0001 
Prognostic factorPFSOS
HR (95% CI)PHR (95% CI)P
Male 1.3 (0.6-2.7) .53 0.7 (0.2-2.3) .60 
Age ≥50 y 1.8 (0.6-5.6) .18 2.2 (0.4-11.4) .23 
Mixed cellularity 0.8 (0.3-2.2) .68 1.1 (0.2-4.8) .92 
Presence of B symptoms 2.9 (1.3-6.7) .0035 4.6 (1.3-15.6) .006 
≥4 Involved sites 2.7 (0.7- 9.5) .028 4.7 (0.7-31.5) .006 
Bulk mediastinum (M/T ≥ 0.35) 0.9-5.7 .026 2.3 (0.6-8.9) .13 
TMTV >147 cm3 5.2 (1.8-14.7) <.0001 7.2 (1.6-33.4) .0001 
U EORTC 5.7 (2.7-12.3) .0013 NR .0039 
U GHSG 2.8 (1.3-6.3) .046 5.3 (1.6-17.6) .075 
U NCCN 3.6 (1.7-7.9) .011 6.7 (2.1-21.6) .034 
Positive iPET2 (DS 4-5) 12 (2.3-63.7) <.0001 13.2 (1.4-128.3) <.0001 

NR, not reached.

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