CD19 expression in matched primary and relapsed clinical samples
Clinical subtype . | Case no., P/R . | Biopsy type . | Time between biopsy (mo) . | CD19 intensity*† . |
---|---|---|---|---|
DBLCL | 1P | BM | 8 | 2 |
1R | BM | 3 | ||
2P | LN | 20 | 3 | |
2R | Mesenteric mass | 3 | ||
3P | Testis | 12 | 3 | |
3R | Penile mass | 3 | ||
4P | LN | 14 | 3 | |
4R | LN | 3 | ||
5P | BM | 8 | 2 | |
5R | LN | 3 | ||
MCL | 6P | Salivary gland | 20 | 3 |
6R | Submandibular | 3 | ||
7P | BM | 11 | 3 | |
7R | LN | 3 | ||
8P | LN | 15 | 3 | |
8R | LN | 3 | ||
9P | Gastrointestinal | 8 | 3 | |
9R | Duodenal bulb | 3 | ||
FL | 10P | LN | 27 | 3 |
10R | LN | 3 | ||
11P | LN | 26 | 3 | |
11R | LN | 3 | ||
Small/chronic LL | 12P | BM | 20 | 3 |
12R | BM | 2 |
Clinical subtype . | Case no., P/R . | Biopsy type . | Time between biopsy (mo) . | CD19 intensity*† . |
---|---|---|---|---|
DBLCL | 1P | BM | 8 | 2 |
1R | BM | 3 | ||
2P | LN | 20 | 3 | |
2R | Mesenteric mass | 3 | ||
3P | Testis | 12 | 3 | |
3R | Penile mass | 3 | ||
4P | LN | 14 | 3 | |
4R | LN | 3 | ||
5P | BM | 8 | 2 | |
5R | LN | 3 | ||
MCL | 6P | Salivary gland | 20 | 3 |
6R | Submandibular | 3 | ||
7P | BM | 11 | 3 | |
7R | LN | 3 | ||
8P | LN | 15 | 3 | |
8R | LN | 3 | ||
9P | Gastrointestinal | 8 | 3 | |
9R | Duodenal bulb | 3 | ||
FL | 10P | LN | 27 | 3 |
10R | LN | 3 | ||
11P | LN | 26 | 3 | |
11R | LN | 3 | ||
Small/chronic LL | 12P | BM | 20 | 3 |
12R | BM | 2 |
BM, bone marrow; DBLCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; LL, lymphocytic leukemia; LN, lymph node; MCL, mantle cell lymphoma; P, primary; R, relapsed.
0 = negative, 1 = weak, 2 = moderate, 3 = strong staining as determined by pathologist review.
In all samples analyzed, >80% tumor cells were CD19+.