Clinical characteristics of the 327 evaluable patients
| Characteristic . | R-CHOP . | R-CHOP + RT . | ||
|---|---|---|---|---|
| No. . | % . | No. . | % . | |
| No. of patients randomly assigned | 163 | 164 | ||
| Ratio of males to females | 94/69 | 102/62 | ||
| Age, y | ||||
| >60 | 55 | 34 | 62 | 38 |
| <60 | 108 | 66 | 102 | 62 |
| mIPI (Miller) | ||||
| 0 | 89 | 55 | 94 | 57 |
| 1 | 65 | 40 | 59 | 36 |
| 2 | 7 | 4 | 9 | 6 |
| 3 | 2 | 1 | ||
| LDH below upper limit of normal | 131 | 80 | 138 | 84 |
| ECOG PS | ||||
| 0-1 | 157 | 161 | ||
| ≥2 | 2 | 3 | ||
| Extranodal sites | 63 | 40 | 66 | 42 |
| Anatomical site | ||||
| Cervical | 85 | 85 | ||
| Axillary | 18 | 12 | ||
| Mediastinal | 9 | 12 | ||
| Inguinal-femoral | 17 | 14 | ||
| Pathology centrally reviewed (263 [80%]) | ||||
| Misdiagnosis | 2 | 2 | ||
| Cell of origin (62% analyzed) | ||||
| Germinal center | 50 | 58 | ||
| Nongerminal center | 27 | 26 | ||
| Undetermined | 15 | 17 | ||
| Characteristic . | R-CHOP . | R-CHOP + RT . | ||
|---|---|---|---|---|
| No. . | % . | No. . | % . | |
| No. of patients randomly assigned | 163 | 164 | ||
| Ratio of males to females | 94/69 | 102/62 | ||
| Age, y | ||||
| >60 | 55 | 34 | 62 | 38 |
| <60 | 108 | 66 | 102 | 62 |
| mIPI (Miller) | ||||
| 0 | 89 | 55 | 94 | 57 |
| 1 | 65 | 40 | 59 | 36 |
| 2 | 7 | 4 | 9 | 6 |
| 3 | 2 | 1 | ||
| LDH below upper limit of normal | 131 | 80 | 138 | 84 |
| ECOG PS | ||||
| 0-1 | 157 | 161 | ||
| ≥2 | 2 | 3 | ||
| Extranodal sites | 63 | 40 | 66 | 42 |
| Anatomical site | ||||
| Cervical | 85 | 85 | ||
| Axillary | 18 | 12 | ||
| Mediastinal | 9 | 12 | ||
| Inguinal-femoral | 17 | 14 | ||
| Pathology centrally reviewed (263 [80%]) | ||||
| Misdiagnosis | 2 | 2 | ||
| Cell of origin (62% analyzed) | ||||
| Germinal center | 50 | 58 | ||
| Nongerminal center | 27 | 26 | ||
| Undetermined | 15 | 17 | ||
ECOG, Eastern Cooperative Oncology Group.