Table 2.

Comparison of cumulative chemotherapy doses in standard therapy arms of COG AAML 0531 and SWOG 1203 trials

Daunorubicin, mg/m2Cytarabine, mg/m2*Etoposide, mg/m2E colil-asparaginase, IU/m2
COG 0531 444 45 600 1750 12 000 
SWOG 1203 270 72 700 
Daunorubicin, mg/m2Cytarabine, mg/m2*Etoposide, mg/m2E colil-asparaginase, IU/m2
COG 0531 444 45 600 1750 12 000 
SWOG 1203 270 72 700 

E coli, Escherichia coli; IU, international unit.

*

Includes induction dose(s) of cytarabine.

A 405 mg/m2 total dose if second course of induction needed due to residual blasts on day +14 bone marrow assessment.

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