Baseline features of children enrolled in ICC-APL-01 and GIMEMA/AIEOP AIDA2000 trials
| Characteristics . | ICC-APL-01 (n = 258) . | AIDA2000 (n = 127) . | P . |
|---|---|---|---|
| Sex, male/female | 121/137 | 77/50 | .01 |
| Age, y | .26 | ||
| Median | 10.3 | 11.9 | |
| Minimum-maximum | 1.1-20.7 | 1.1-18.0 | |
| WBC count, ×109/L | .13 | ||
| Median | 6.3 | 3.6 | |
| Minimum-maximum | 0.08-339 | 0.2-187.0 | |
| Platelet count, ×109/L | .78 | ||
| Median | 23.0 | 27.56 | |
| Minimum-maximum | 2.0-262.0 | 7.0-250.0 | |
| FAB type, M3/M3v/NA | 210/44/4 | 105/22 | 1.0 |
| PML/RARα isoform | |||
| BCR, 1/2/3/NA | 110/7/102/39 | 50/6/37/34 | .28 |
| SR/HR, % | 149 (58)/109 (42) | 85 (67)/42 (33) | .09 |
| Characteristics . | ICC-APL-01 (n = 258) . | AIDA2000 (n = 127) . | P . |
|---|---|---|---|
| Sex, male/female | 121/137 | 77/50 | .01 |
| Age, y | .26 | ||
| Median | 10.3 | 11.9 | |
| Minimum-maximum | 1.1-20.7 | 1.1-18.0 | |
| WBC count, ×109/L | .13 | ||
| Median | 6.3 | 3.6 | |
| Minimum-maximum | 0.08-339 | 0.2-187.0 | |
| Platelet count, ×109/L | .78 | ||
| Median | 23.0 | 27.56 | |
| Minimum-maximum | 2.0-262.0 | 7.0-250.0 | |
| FAB type, M3/M3v/NA | 210/44/4 | 105/22 | 1.0 |
| PML/RARα isoform | |||
| BCR, 1/2/3/NA | 110/7/102/39 | 50/6/37/34 | .28 |
| SR/HR, % | 149 (58)/109 (42) | 85 (67)/42 (33) | .09 |
NA, not available.