Tissue/Cell Types Expressing IL-11
| Tissue . | Cell Type/Cell Lines . | Inducers . |
|---|---|---|
| CNS | Hippocampal neurons (H19-7)10 | IL-1α |
| Spinal motor and sympathetic neurons10 | ||
| Astrocytic glioblastoma (U373, U87)163 | IL-1β, PMA, calcium inophore | |
| Thymus | Myeloid? (T2)2 | LPS |
| Lung | Fibroblast (MRC5, CCL202)16 | IL-1α, TGF-β1-2, PMA, RSV, Ca++/calmodulin |
| Epithelial (9HTE, A549)15 17 | Rhinovirus, parainfluenza type 3, histamine (H1) | |
| Muscle cells | IL-1α, TGF-β1 | |
| Bone | Fibroblast (P-34, KM102)5-7 71 | IL-1α, PMA, PKC |
| Osteosarcoma cell lines13 32 | IL-1α, TGF-β1, PTH, PTHrP, cAMP, PKC | |
| Osteoblast86 | IL-1α, TGF-β1, TNF-α, PGE2, PTH, 1α, 25(OH)2D3 | |
| Connective tissues | Chondrocyte, synoviocyte14 | IL-1β, TGF-β1, PMA, PKC |
| Vein endothelial cells32 | IL-1α, TGF-β1,2, PMA | |
| Uterus | Fibroblast | IL-1α, PTHrP |
| Trophoblast (TPA30-1)5 | IL-1α, PMA | |
| Endometriotic & endometrial tissues164 165 | ||
| Skin | Keratinocyte166 | |
| Melanoma cell lines167 | ||
| Sarcoidosis (multinucleated giant cells)166 | ||
| Testis | Round spermatids10 |
| Tissue . | Cell Type/Cell Lines . | Inducers . |
|---|---|---|
| CNS | Hippocampal neurons (H19-7)10 | IL-1α |
| Spinal motor and sympathetic neurons10 | ||
| Astrocytic glioblastoma (U373, U87)163 | IL-1β, PMA, calcium inophore | |
| Thymus | Myeloid? (T2)2 | LPS |
| Lung | Fibroblast (MRC5, CCL202)16 | IL-1α, TGF-β1-2, PMA, RSV, Ca++/calmodulin |
| Epithelial (9HTE, A549)15 17 | Rhinovirus, parainfluenza type 3, histamine (H1) | |
| Muscle cells | IL-1α, TGF-β1 | |
| Bone | Fibroblast (P-34, KM102)5-7 71 | IL-1α, PMA, PKC |
| Osteosarcoma cell lines13 32 | IL-1α, TGF-β1, PTH, PTHrP, cAMP, PKC | |
| Osteoblast86 | IL-1α, TGF-β1, TNF-α, PGE2, PTH, 1α, 25(OH)2D3 | |
| Connective tissues | Chondrocyte, synoviocyte14 | IL-1β, TGF-β1, PMA, PKC |
| Vein endothelial cells32 | IL-1α, TGF-β1,2, PMA | |
| Uterus | Fibroblast | IL-1α, PTHrP |
| Trophoblast (TPA30-1)5 | IL-1α, PMA | |
| Endometriotic & endometrial tissues164 165 | ||
| Skin | Keratinocyte166 | |
| Melanoma cell lines167 | ||
| Sarcoidosis (multinucleated giant cells)166 | ||
| Testis | Round spermatids10 |