Characteristics of CD34-Enriched and Transduced Cells
| . | % CD34+ Post Column Selection . | % CD34+ Post Transduction . | CD34+ Cells Post:Pre Transduction . |
|---|---|---|---|
| Peripheral blood | |||
| 6H | 70.8 (14.5) | 65 (19.4) | 0.5 (14) |
| ST | 50 (29) | 38 (33) | 0.44 (10) |
| IL-3, 6, SCF | 53.2 (29) | 64.7 (26) | 1.1 |
| Bone Marrow | |||
| 6H | 67.6 (16) | 58.7 (26) | 0.43 (30) |
| ST | 67 (15) | 53 (8.5) | 0.62 (23) |
| IL-3, 6, SCF | 64 (11) | 73.3 (5.2) | 1.2 |
| . | % CD34+ Post Column Selection . | % CD34+ Post Transduction . | CD34+ Cells Post:Pre Transduction . |
|---|---|---|---|
| Peripheral blood | |||
| 6H | 70.8 (14.5) | 65 (19.4) | 0.5 (14) |
| ST | 50 (29) | 38 (33) | 0.44 (10) |
| IL-3, 6, SCF | 53.2 (29) | 64.7 (26) | 1.1 |
| Bone Marrow | |||
| 6H | 67.6 (16) | 58.7 (26) | 0.43 (30) |
| ST | 67 (15) | 53 (8.5) | 0.62 (23) |
| IL-3, 6, SCF | 64 (11) | 73.3 (5.2) | 1.2 |
Abbreviations: 6H, cells transduced for 6 hours without growth factors; ST, cells transduced for 72 hours in the presence of autologous stroma; IL-3, 6, SCF, cells transduced for 72 hours in the presence of IL-3, IL-6, and SCF.
Data from Dunbar et al.4