| A. No regular need for transfusion, platelet count ≥100 × 109/L, no evidence of inflammation, and no concomitant chemotherapy (all of these) |
| Start with 200 to 250 IU/kg/wk SC (divided in 3 administrations) |
| B. Regular need for transfusion, platelet count <100 × 109/L, inflammatory condition, or concomitant chemotherapy (one of these) |
| Start with 400 to 500 IU/kg/wk SC (divided in 3 administrations) |
| A. No regular need for transfusion, platelet count ≥100 × 109/L, no evidence of inflammation, and no concomitant chemotherapy (all of these) |
| Start with 200 to 250 IU/kg/wk SC (divided in 3 administrations) |
| B. Regular need for transfusion, platelet count <100 × 109/L, inflammatory condition, or concomitant chemotherapy (one of these) |
| Start with 400 to 500 IU/kg/wk SC (divided in 3 administrations) |