Table 1.

Characteristics of BM and PBSC Recipients

BM Recipients (n = 29)PBSC Recipients (n = 20)P Value*
Patient age (yr) 38 (18-67) 37 (29-61) .68 
Day (after transplant) of the lymphocyte analysis 57 (48-69) 55 (45-67) .17 
Patient sex (males/females) 12/17 (41%/59%) 13/7 (65%/35%) .15 
Donor sex (males/females) 10/19 (34%/66%) 8/12 (40%/60%) .77 
No. of patients with history of splenectomy 1 (3%) 0 (0%) 1.00 
No. of CMV seropositive patients (pretransplant) 17 (59%) 9 (45%) .25 
No. of CMV seropositive donors (pretransplant) 17 (59%) 8 (40%) .15 
No. of patients with grade 2-3 acute GVHD 20 (69%) 17 (85%) .31 
No. of patients treated with a corticosteroidρ at the time of lymphocyte analysis 20 (69%) 16 (80%) .52 
No. of patients receiving CMV-specific CD8 T cells9 before the time of lymphocyte analysis 1 (3%) 2 (10%) .56 
No. of patients treated with ganciclovir at the time of lymphocyte analysis 13 (45%) 6 (30%) .38 
No. of patients treated with intravenous Ig between days 0 and 80 3 (10%) 4 (20%) .42 
BM Recipients (n = 29)PBSC Recipients (n = 20)P Value*
Patient age (yr) 38 (18-67) 37 (29-61) .68 
Day (after transplant) of the lymphocyte analysis 57 (48-69) 55 (45-67) .17 
Patient sex (males/females) 12/17 (41%/59%) 13/7 (65%/35%) .15 
Donor sex (males/females) 10/19 (34%/66%) 8/12 (40%/60%) .77 
No. of patients with history of splenectomy 1 (3%) 0 (0%) 1.00 
No. of CMV seropositive patients (pretransplant) 17 (59%) 9 (45%) .25 
No. of CMV seropositive donors (pretransplant) 17 (59%) 8 (40%) .15 
No. of patients with grade 2-3 acute GVHD 20 (69%) 17 (85%) .31 
No. of patients treated with a corticosteroidρ at the time of lymphocyte analysis 20 (69%) 16 (80%) .52 
No. of patients receiving CMV-specific CD8 T cells9 before the time of lymphocyte analysis 1 (3%) 2 (10%) .56 
No. of patients treated with ganciclovir at the time of lymphocyte analysis 13 (45%) 6 (30%) .38 
No. of patients treated with intravenous Ig between days 0 and 80 3 (10%) 4 (20%) .42 
*

P value for the difference between BM and PBSC recipients; tested by Wilcoxon-Mann-Whitney rank-sum test in the case of ordinal or interval variables and by Fisher exact test in the case of nominal variables.

Median (range).

No patient developed grade 4 acute GVHD.

ρ As treatment for acute GVHD.

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