Statistical Correlation Between Age and Different Phenotypic Determinations of Protein S and C4bBP-β+ in Genetically Determined Protein S Deficiency
| Group . | Total Protein S Antigen . | Free Protein S Antigen . | C4bBP-β+ Antigen . |
|---|---|---|---|
| Normal family members | r = .42 (n = 78, P = .001) | r = .07 (n = 78, P = .53) | r = .405 (n = 67, P = .0006) |
| Protein S–deficient family members* | r = .56 (n = 31, P = .001) | r = .24 (n = 31, P = .19) | r = .43 (n = 21, P = .053) |
| Group . | Total Protein S Antigen . | Free Protein S Antigen . | C4bBP-β+ Antigen . |
|---|---|---|---|
| Normal family members | r = .42 (n = 78, P = .001) | r = .07 (n = 78, P = .53) | r = .405 (n = 67, P = .0006) |
| Protein S–deficient family members* | r = .56 (n = 31, P = .001) | r = .24 (n = 31, P = .19) | r = .43 (n = 21, P = .053) |
The relationship is shown between the listed variable and age, calculated using Pearson's correlation coefficient (r ).
Includes only protein S–deficient family members not receiving oral anticoagulant treatment at time of testing. All protein S–deficient individuals had the Gly295Val mutation.