Table 3. Lymphocyte Subsets After... | American Society of Hematology

Table 3.

Lymphocyte Subsets After Completion of Chemotherapy in Patients With and Without Thymic Rebound

Subset	Time	Thymic Rebound^3-150
	Posttherapy	+	−	P Value
CD8⁺CD3⁺	3 mos	594 ± 244	476 ± 197	.78
CD8⁺CD3⁺	6 mos	695 ± 197	331 ± 184	.20
CD8⁺CD45RA⁺	3 mos	93 ± 37	46 ± 12	.32
CD8⁺CD45RA⁺	6 mos	217 ± 52	116 ± 43	.25
CD4⁺CD3⁺	3 mos	343 ± 119	182 ± 25	.47
CD4⁺CD3⁺	6 mos	507 ± 77	203 ± 39^3-151	.006
CD4⁺CD45RA⁺	3 mos	106 ± 21	13 ± 4^3-151	.004
CD4⁺CD45RA⁺	6 mos	320 ± 123	23 ± 9^3-151	.001

Subset	Time	Thymic Rebound^3-150
	Posttherapy	+	−	P Value
CD8⁺CD3⁺	3 mos	594 ± 244	476 ± 197	.78
CD8⁺CD3⁺	6 mos	695 ± 197	331 ± 184	.20
CD8⁺CD45RA⁺	3 mos	93 ± 37	46 ± 12	.32
CD8⁺CD45RA⁺	6 mos	217 ± 52	116 ± 43	.25
CD4⁺CD3⁺	3 mos	343 ± 119	182 ± 25	.47
CD4⁺CD3⁺	6 mos	507 ± 77	203 ± 39^3-151	.006
CD4⁺CD45RA⁺	3 mos	106 ± 21	13 ± 4^3-151	.004
CD4⁺CD45RA⁺	6 mos	320 ± 123	23 ± 9^3-151	.001

F3-150

Thymic rebound was determined based on either a twofold increase in thymic volume during the first year after chemotherapy compared with thymic volume pretherapy as measured by CT scanning or thymic uptake by gallium⁶⁷ scanning as delineated in Materials and Methods.

F3-151

P value using Mann-Whitney U test.

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