Table 1.

Binding of Radiolabeled IL-10 to Fresh B-CLL Cells

ExperimentCPMCPM*
1 2,370 424 
2 3,100 459 
3 3,539 1,273 
4 3,040 2,034 
5 3,301 1,196 
6 4,691 2,070 
7 2,126 711 
8 3,215 695 
9 2,518 992 
Mean ± SEM 3,100 ± 252 1,023 ± 205 
P value† <.0005 
   
ExperimentCPMCPM*
1 2,370 424 
2 3,100 459 
3 3,539 1,273 
4 3,040 2,034 
5 3,301 1,196 
6 4,691 2,070 
7 2,126 711 
8 3,215 695 
9 2,518 992 
Mean ± SEM 3,100 ± 252 1,023 ± 205 
P value† <.0005 
   

Binding of 125I-recombinant human IL-10 to 5 × 106 freshly isolated MNCs from 9 patients with B-CLL (mean of assays performed in triplicate).

*

With 1,000-fold molar excess unlabeled IL-10.

†

Student's paired t-test.

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