Patient Characteristics
| Parameter . | Remission n = 66 . | Relapse . | PIF . | Total . |
|---|---|---|---|---|
| . | . | n = 94 . | n = 14 . | n = 174 . |
| Age (yr) | ||||
| <18/≥18 | 33/33 | 33/59 | 5/9 | 71/103 |
| Median, range | 17, 1-47 | 21, .5-51 | 31, 7-54 | 20, .5-54 |
| Sex (male/female) | 34/32 | 53/41 | 11/3 | 98/76 |
| AML/ALL/Hybrid AL | 21/41/4 | 40/49/5 | 13/1/0 | 74/91/9 |
| History of extramedullary leukemia | 19 | 36 | 3 | 58 |
| WBC at diagnosis (×109/L) | ||||
| Median, range | 10, .7-195 | 15, .7-650 | 17, 1.3-288 | 13, .7-650 |
| NA | 11 | 16 | 4 | 31 |
| BM cytogenetics* | ||||
| Unfavorable | 8 | 19 | 4 | 31 |
| Intermediate | 20 | 25 | 6 | 51 |
| Favorable | 3 | 8 | 0 | 11 |
| NA | 35 | 42 | 4 | 81 |
| CR1 duration* (mo) | ||||
| <12/≥12 | 20/34 | 52/38 | — | 72/72 |
| Median, range | 20, 1-156 | 10, 1-126 | — | 11, 1-156 |
| NA | 1 | 4 | — | 5 |
| CMV Seropositive patient | ||||
| Pretransplant | 27 | 44 | 11 | 82 |
| Donor | ||||
| HLA-minor mismatched | 22 | 34 | 6 | 62 |
| Parameter . | Remission n = 66 . | Relapse . | PIF . | Total . |
|---|---|---|---|---|
| . | . | n = 94 . | n = 14 . | n = 174 . |
| Age (yr) | ||||
| <18/≥18 | 33/33 | 33/59 | 5/9 | 71/103 |
| Median, range | 17, 1-47 | 21, .5-51 | 31, 7-54 | 20, .5-54 |
| Sex (male/female) | 34/32 | 53/41 | 11/3 | 98/76 |
| AML/ALL/Hybrid AL | 21/41/4 | 40/49/5 | 13/1/0 | 74/91/9 |
| History of extramedullary leukemia | 19 | 36 | 3 | 58 |
| WBC at diagnosis (×109/L) | ||||
| Median, range | 10, .7-195 | 15, .7-650 | 17, 1.3-288 | 13, .7-650 |
| NA | 11 | 16 | 4 | 31 |
| BM cytogenetics* | ||||
| Unfavorable | 8 | 19 | 4 | 31 |
| Intermediate | 20 | 25 | 6 | 51 |
| Favorable | 3 | 8 | 0 | 11 |
| NA | 35 | 42 | 4 | 81 |
| CR1 duration* (mo) | ||||
| <12/≥12 | 20/34 | 52/38 | — | 72/72 |
| Median, range | 20, 1-156 | 10, 1-126 | — | 11, 1-156 |
| NA | 1 | 4 | — | 5 |
| CMV Seropositive patient | ||||
| Pretransplant | 27 | 44 | 11 | 82 |
| Donor | ||||
| HLA-minor mismatched | 22 | 34 | 6 | 62 |
Abbreviations: AL, acute leukemia; ALL, acute lymphoid leukemia; AML, acute myeloid leukemia; BM, bone marrow; CMV, cytomegalovirus; NA, not available; PIF, primary induction failure; WBC, white blood cells.
See text for definitions.