Effect of Culture Supernatant From CD4+ or CD8+ DC-Stimulated T Cells on Colony Growth by Autologous CML Cells
Patient No. . | Medium . | CD4+ Supernatant . | CD8+ Supernatant . |
---|---|---|---|
1 | 129 ± 14 | 78 ± 16 | 97 ± 7 |
2 | 247 + 27 | 120 ± 34 | 205 ± 16 |
3 | 376 ± 24 | 164 ± 32 | 324 ± 42 |
P ≤ .005 | P = NS |
Patient No. . | Medium . | CD4+ Supernatant . | CD8+ Supernatant . |
---|---|---|---|
1 | 129 ± 14 | 78 ± 16 | 97 ± 7 |
2 | 247 + 27 | 120 ± 34 | 205 ± 16 |
3 | 376 ± 24 | 164 ± 32 | 324 ± 42 |
P ≤ .005 | P = NS |
One hundred thousand autologous CML BMMNCs were cultured in Methocult medium with 30% T-cell culture supernatant or control medium. Results represent the mean ± SD of triplicate cultures. Statistical significance determined using the Student's t-test.
Abbreviation: NS, not significant (P ≥ .05).