Clinical Characteristics According to Iron Category
| . | Group I: Ferritin Not Elevated . | Group II: Ferritin Elevated and Transferrin Saturation <70% (n = 17) . | Group III: Ferritin Elevated and Transferrin Saturation >70% . | P . |
|---|---|---|---|---|
| . | (n = 35) . | . | (n = 4) . | . |
| Age (yr; mean ± SD) | 61 ± 14 | 60 ± 11 | 61 ± 10 | .96 |
| Sex (M:F) | 14:21 | 10:7 | 4:0 | .052 |
| Beer consumption (liters; median and range) | 19,200 | 10,944 | 35,040 | .3 |
| (1,920-94,896) | (2,880-90,000) | (15,600-113,400) | ||
| Years of beer consumption (mean ± SD) | 37 ± 15 | 33 ± 12 | 33 ± 8 | .7 |
| Abstention from beer (days; median and range) | 4 (1->30) | 2 (1->30) | 2 (1-3) | .4 |
| Serum ferritin (μg/L; geometric mean and SD range) | 86 (28-260) | 478 (272-838) | 1,621 (925-2,844) | — |
| Transferrin saturation (%; mean ± SD) | 37 ± 14 | 45 ± 10 | 79 ± 1 | — |
| Ferritin:AST ratio (median and range) | 4.5 (0.2-18.3) | 17.0 (2.9-39.5) | 42.5 (33.8-51.2) | <.0005 |
| Hemoglobin (g/dL; mean ± SD) | 13.7 ± 1.27-150 | 14.3 ± 0.9 | 14.3 ± 1.27-151 | .13 |
| Reticulocytes (mean ± SD) | 22,000 ± 13,2007-150 | 29,600 ± 18,500 | 23,900 ± 3,6007-151 | .13 |
| Erythrocyte sedimentation rate (mm/h; median and range) | 12 (0-90)7-150 | 10 (2-115) | 20 (5-55)7-151 | .7 |
| Lactate dehydrogenase (U/L; mean ± SD) | 155 ± 467-152 | 170 ± 53ρ | 153 ± 367-151 | .6 |
| Protein (g/L; mean ± SD) | 76 ± 9 | 77 ± 7 | 84 ± 5 | .3 |
| Albumin (g/L; mean ± SD) | 41 ± 6 | 42 ± 4 | 44 ± 5 | .4 |
| Bilirubin (mmol/L; mean ± SD) | 7.0 ± 4.6 | 8.9 ± 5.5 | 11.5 ± 3.0 | .14 |
| Alkaline phosphatase (U/L; median and range) | 93 (34-153) | 84 (58-185) | 77 (70-99) | .4 |
| Alanine aminotransferase (U/L; median and range) | 18 (13-51) | 26 (11-98) | 28 (18-124) | .02 |
| Aspartate aminotransferase (U/L; median and range) | 23 (13-58) | 28 (18-94) | 32 (24-125) | .027 |
| Gamma glutamyltransferase (U/L; median and range) | 15 (3-84) | 25 (10-123) | 49 (27-171) | .005 |
| Vitamin C (ng/108 white blood cells; median and range) | 44 (35-93)7-155 | 41 (19-70)7-154 | 36 (25-48)7-167 | .3 |
| . | Group I: Ferritin Not Elevated . | Group II: Ferritin Elevated and Transferrin Saturation <70% (n = 17) . | Group III: Ferritin Elevated and Transferrin Saturation >70% . | P . |
|---|---|---|---|---|
| . | (n = 35) . | . | (n = 4) . | . |
| Age (yr; mean ± SD) | 61 ± 14 | 60 ± 11 | 61 ± 10 | .96 |
| Sex (M:F) | 14:21 | 10:7 | 4:0 | .052 |
| Beer consumption (liters; median and range) | 19,200 | 10,944 | 35,040 | .3 |
| (1,920-94,896) | (2,880-90,000) | (15,600-113,400) | ||
| Years of beer consumption (mean ± SD) | 37 ± 15 | 33 ± 12 | 33 ± 8 | .7 |
| Abstention from beer (days; median and range) | 4 (1->30) | 2 (1->30) | 2 (1-3) | .4 |
| Serum ferritin (μg/L; geometric mean and SD range) | 86 (28-260) | 478 (272-838) | 1,621 (925-2,844) | — |
| Transferrin saturation (%; mean ± SD) | 37 ± 14 | 45 ± 10 | 79 ± 1 | — |
| Ferritin:AST ratio (median and range) | 4.5 (0.2-18.3) | 17.0 (2.9-39.5) | 42.5 (33.8-51.2) | <.0005 |
| Hemoglobin (g/dL; mean ± SD) | 13.7 ± 1.27-150 | 14.3 ± 0.9 | 14.3 ± 1.27-151 | .13 |
| Reticulocytes (mean ± SD) | 22,000 ± 13,2007-150 | 29,600 ± 18,500 | 23,900 ± 3,6007-151 | .13 |
| Erythrocyte sedimentation rate (mm/h; median and range) | 12 (0-90)7-150 | 10 (2-115) | 20 (5-55)7-151 | .7 |
| Lactate dehydrogenase (U/L; mean ± SD) | 155 ± 467-152 | 170 ± 53ρ | 153 ± 367-151 | .6 |
| Protein (g/L; mean ± SD) | 76 ± 9 | 77 ± 7 | 84 ± 5 | .3 |
| Albumin (g/L; mean ± SD) | 41 ± 6 | 42 ± 4 | 44 ± 5 | .4 |
| Bilirubin (mmol/L; mean ± SD) | 7.0 ± 4.6 | 8.9 ± 5.5 | 11.5 ± 3.0 | .14 |
| Alkaline phosphatase (U/L; median and range) | 93 (34-153) | 84 (58-185) | 77 (70-99) | .4 |
| Alanine aminotransferase (U/L; median and range) | 18 (13-51) | 26 (11-98) | 28 (18-124) | .02 |
| Aspartate aminotransferase (U/L; median and range) | 23 (13-58) | 28 (18-94) | 32 (24-125) | .027 |
| Gamma glutamyltransferase (U/L; median and range) | 15 (3-84) | 25 (10-123) | 49 (27-171) | .005 |
| Vitamin C (ng/108 white blood cells; median and range) | 44 (35-93)7-155 | 41 (19-70)7-154 | 36 (25-48)7-167 | .3 |