Table 2. Comparison of Phagocytic Levels... | American Society of Hematology

Table 2.

Comparison of Phagocytic Levels for Monkey E Opsonized With a Mouse MoAb Specific for CR1 (7G9) or Band 3 (A9D3) Followed by a Saturating Input of Rabbit Antimouse IgG

Mouse MoAb	Molecules of Rabbit IgG Bound per E	%P	PI	Experiment No.
—	<500	.43	.54	1
7G9	13,900	.1	.1	1
A9D3^*	14,700	6.6	9.2	1
A9D3^†	8,400	6.5	8.8	1
—	<500	3.5	4.1	2
7G9	12,200	4.1	5.0	2
A9D3^*	11,000	14.7	19.5	2
A9D3^†	7,050	24.0	34.0	2
—	<500	1.6	2.5	3
7G9	9,300	3.5	4.7	3
A9D3^*	12,900	10.5	23.0	3
A9D3^‡	3,400	9.0	17.9	3

Mouse MoAb	Molecules of Rabbit IgG Bound per E	%P	PI	Experiment No.
—	<500	.43	.54	1
7G9	13,900	.1	.1	1
A9D3^*	14,700	6.6	9.2	1
A9D3^†	8,400	6.5	8.8	1
—	<500	3.5	4.1	2
7G9	12,200	4.1	5.0	2
A9D3^*	11,000	14.7	19.5	2
A9D3^†	7,050	24.0	34.0	2
—	<500	1.6	2.5	3
7G9	9,300	3.5	4.7	3
A9D3^*	12,900	10.5	23.0	3
A9D3^‡	3,400	9.0	17.9	3

Abbreviations: P, phagocytosis; PI, phagocytic index.

An 8,000-fold dilution of MoAb was used.

†

A 16,000-fold dilution of MoAb was used.

‡

A 32,000-fold dilution of MoAb was used.

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