Tumorigenic Properties of U937 and RU Cell Clones in scid/scid Mice
| Clone* . | Fraction of Animals With Tumors† . | Tumorigenic Capacity (%)‡ . | Delay (d)ρ . | Tumor Section (mm2 )1-155 . |
|---|---|---|---|---|
| U937 | 20/25 | 80 ± 20 | 14 | 68 |
| RU1 | 8/29 | 28 ± 17 | 18 | 14 |
| RU2 | 11/29 | 38 ± 17 | 15 | 6 |
| RU3 | 21/25 | 84 ± 21 | 13 | 107 |
| RU4 | 0/15 | 0 | NR | NR |
| Clone* . | Fraction of Animals With Tumors† . | Tumorigenic Capacity (%)‡ . | Delay (d)ρ . | Tumor Section (mm2 )1-155 . |
|---|---|---|---|---|
| U937 | 20/25 | 80 ± 20 | 14 | 68 |
| RU1 | 8/29 | 28 ± 17 | 18 | 14 |
| RU2 | 11/29 | 38 ± 17 | 15 | 6 |
| RU3 | 21/25 | 84 ± 21 | 13 | 107 |
| RU4 | 0/15 | 0 | NR | NR |
Abbreviation: NR, not relevant.
Ten million cells injected subcutaneously in the flank fat pads.
Number of animals developing a palpable tumor within 2 months over total number of treated animals (pooled data from three experiments).
Percentage of tumor-bearing animals (average value and SD from three experiments).
ρ Average time after which at least half of the tumor appeared in a series.
Product of main diameters.