Table 1.

Summary of Mutations in the V Regions Expressed in Vk-Bearing IgM+IgD+, IgM++IgD+, IgM-Only, and Class-Switched B Cells Derived From the PB of a 27-Year-Old Person

Cell Populationn*Range% Mutation
IgM+IgD+ 0-1 0.2 
IgM++IgD+ 11 0-6 0.4 
IgM++IgD 0-12 1.7 
IgG+ and IgA+ 3-23 4.2 
Cell Populationn*Range% Mutation
IgM+IgD+ 0-1 0.2 
IgM++IgD+ 11 0-6 0.4 
IgM++IgD 0-12 1.7 
IgG+ and IgA+ 3-23 4.2 
*

Number of cDNA clones.

Range of mutations per gene.

The PCR error rate of 0.15%16 was not subtracted from the values.

Close Modal

or Create an Account

Close Modal
Close Modal