Factor V Leiden and Metabolic Risk Factors: Separate and Combined Effects on MI
| Risk Factors4-150 . | Factor V Genotype . | Patients . | Controls . | OR4-151 . | CI95 . |
|---|---|---|---|---|---|
| None | Wild-type | 21 | 260 | 1 | |
| None | Leiden | 4 | 14 | 3.5 | 1.1-11.7 |
| One or more | Wild-type | 55 | 108 | 6.3 | 3.6-10.9 |
| One or more | Leiden | 4 | 2 | 24.8 | 4.5-194 |
| Risk Factors4-150 . | Factor V Genotype . | Patients . | Controls . | OR4-151 . | CI95 . |
|---|---|---|---|---|---|
| None | Wild-type | 21 | 260 | 1 | |
| None | Leiden | 4 | 14 | 3.5 | 1.1-11.7 |
| One or more | Wild-type | 55 | 108 | 6.3 | 3.6-10.9 |
| One or more | Leiden | 4 | 2 | 24.8 | 4.5-194 |
Obesity (BMI ≥ 27.3); treated hypertension, diabetes, or hypercholesterolemia; or combinations of same (these data were missing in four controls).
All odds are relative to the reference category, ie, those who did not have any of these four risk factors and did not carry the mutation. Age-adjusted logistic regression yielded similar odds ratios.