Table 1. Initial Stage and Previous... | American Society of Hematology

Table 1.

Initial Stage and Previous Therapy Characteristics

Characteristic	CCNU	BCNU	FTBI	Total
	n = 19	n = 74	n = 26	n = 119
	N Patients

Stage at diagnosis^*
I	0	1	0	1
II	8	29	3	40
III	6	31	8	45
IV	5	13	15	33
Constitutional symptoms at
diagnosis	9	42	19	70
No. of drugs in initial course
of treatment^†
Four or fewer	7	29	9	45
More than four	10	31	17	58
Initial remission duration^†
Induction failure	8	12	9	29
61-365 days	2	23	10	35
>365 days	7	25	7	39
Prior RT history^*
None	6	17	23	46
Single course of RT alone	2	15	0	17
Combined modality
treatment	11	42	3	56
Relapse in previously
irradiated sites^*
RT site only	6	20	0	26
Within and outside RT site	4	21	2	27
Total no. of prior CT drugs
Four or fewer	6	25	7	38
More than four	13	49	19	81
No. prior CT courses^†
One	12	38	21	71
Two+	5	22	5	32
RT alone first course^‡	2	14	0	16
No. cytoreductive regimens
None	4	2	0	6
One	9	51	18	78
Two or more	6	12	7	25
RT	2	12	6	20

Characteristic	CCNU	BCNU	FTBI	Total
	n = 19	n = 74	n = 26	n = 119
	N Patients

Stage at diagnosis^*
I	0	1	0	1
II	8	29	3	40
III	6	31	8	45
IV	5	13	15	33
Constitutional symptoms at
diagnosis	9	42	19	70
No. of drugs in initial course
of treatment^†
Four or fewer	7	29	9	45
More than four	10	31	17	58
Initial remission duration^†
Induction failure	8	12	9	29
61-365 days	2	23	10	35
>365 days	7	25	7	39
Prior RT history^*
None	6	17	23	46
Single course of RT alone	2	15	0	17
Combined modality
treatment	11	42	3	56
Relapse in previously
irradiated sites^*
RT site only	6	20	0	26
Within and outside RT site	4	21	2	27
Total no. of prior CT drugs
Four or fewer	6	25	7	38
More than four	13	49	19	81
No. prior CT courses^†
One	12	38	21	71
Two+	5	22	5	32
RT alone first course^‡	2	14	0	16
No. cytoreductive regimens
None	4	2	0	6
One	9	51	18	78
Two or more	6	12	7	25
RT	2	12	6	20

Abbreviations: CT, chemotherapy; RT, radiotherapy.

Significant (P ≤ .05) differences in distribution.

Excludes 16 patients who received RT alone as primary treatment.

Includes 16 patients who received RT alone as primary treatment.