Differential Features Among CSR and NR Subjects
| . | SR . | NR . | P . |
|---|---|---|---|
| . | (28 cases) . | (42 cases) . | . |
| Mean age (yr) | 13.7 ± 5.7 | 14.2 ± 7.0 | NS |
| Sex (M/F) | 10/18 | 23/19 | NS |
| Disease duration | 59.7 ± 31.8 | 63.9 ± 36.5 | NS |
| Splenectomy | 14 (50%) | 20 (47.6%) | NS |
| ALT* | 119.3 ± 123 | 107.0 ± 49.4 | NS |
| Ferritin† | 2,919 ± 1,934 | 3,457 ± 1,767 | NS |
| LIC‡ | 53.96 ± 39.43 | 84.38 ± 65.51 | .06 |
| HCV-RNA positive | 23 (82.1%) | 40 (95.2%) | NS |
| HCV type | |||
| 1b | 11 (39.3%) | 30 (71.4%) | |
| Non-1b/mixed | 12 (42.8%) | 10 (23.8%) | |
| Untypable | 5 (17.9%) | 2 (4.8%) | .02 |
| Liver histology | |||
| CH | 24 (85.7%) | 19 (45.2%) | |
| CH with fibrosis | 3 (10.7%) | 13 (31.0%) | |
| CH with cirrhosis | 1 (3.6%) | 10 (23.8%) | .002 |
| Histologic grading of liver siderosis | |||
| Grade 0 or 1 | 6 (21.4%) | 8 (19.0%) | |
| Grade 2 | 15 (53.6%) | 17 (40.5%) | |
| Grade 3 or 4 | 7 (25.0%) | 17 (40.5%) | NS |
| . | SR . | NR . | P . |
|---|---|---|---|
| . | (28 cases) . | (42 cases) . | . |
| Mean age (yr) | 13.7 ± 5.7 | 14.2 ± 7.0 | NS |
| Sex (M/F) | 10/18 | 23/19 | NS |
| Disease duration | 59.7 ± 31.8 | 63.9 ± 36.5 | NS |
| Splenectomy | 14 (50%) | 20 (47.6%) | NS |
| ALT* | 119.3 ± 123 | 107.0 ± 49.4 | NS |
| Ferritin† | 2,919 ± 1,934 | 3,457 ± 1,767 | NS |
| LIC‡ | 53.96 ± 39.43 | 84.38 ± 65.51 | .06 |
| HCV-RNA positive | 23 (82.1%) | 40 (95.2%) | NS |
| HCV type | |||
| 1b | 11 (39.3%) | 30 (71.4%) | |
| Non-1b/mixed | 12 (42.8%) | 10 (23.8%) | |
| Untypable | 5 (17.9%) | 2 (4.8%) | .02 |
| Liver histology | |||
| CH | 24 (85.7%) | 19 (45.2%) | |
| CH with fibrosis | 3 (10.7%) | 13 (31.0%) | |
| CH with cirrhosis | 1 (3.6%) | 10 (23.8%) | .002 |
| Histologic grading of liver siderosis | |||
| Grade 0 or 1 | 6 (21.4%) | 8 (19.0%) | |
| Grade 2 | 15 (53.6%) | 17 (40.5%) | |
| Grade 3 or 4 | 7 (25.0%) | 17 (40.5%) | NS |