Previous Chemotherapy, Impact on Mobilization Total Yields
. | Previous Chemotherapy/Treatment5-150 . | |||||
---|---|---|---|---|---|---|
. | Extensive . | Nonextensive . | . | . | ||
. | Filgrastim Alone . | All Combinations . | Filgrastim Alone . | All Combinations . | . | . |
CD34+ (106/kg) | ||||||
N | 5 | 18 | 5 | 7 | ||
Median | 0.28 | 1.76 | 3.68 | 5.27 | ||
Range | (0.03-3.39) | (0.09-12.04) | (2.95-20.68) | (1.79-8.94) | ||
GM-CFC (104/kg) | ||||||
N | 5 | 18 | 5 | 7 | ||
Median | 5.01 | 20.43 | 40.21 | 47.93 | ||
Range | (0.10-49.64) | (0.13-223.76) | (18.7-123.07) | (9.11-121.00) | ||
BFU-E (104/kg) | ||||||
N | 5 | 18 | 5 | 7 | ||
Median | 8.90 | 36.87 | 64.92 | 122.71 | ||
Range | (0.36-21.28) | (0.00-601.46) | (12.50-131.55) | (35.82-283.00) |
. | Previous Chemotherapy/Treatment5-150 . | |||||
---|---|---|---|---|---|---|
. | Extensive . | Nonextensive . | . | . | ||
. | Filgrastim Alone . | All Combinations . | Filgrastim Alone . | All Combinations . | . | . |
CD34+ (106/kg) | ||||||
N | 5 | 18 | 5 | 7 | ||
Median | 0.28 | 1.76 | 3.68 | 5.27 | ||
Range | (0.03-3.39) | (0.09-12.04) | (2.95-20.68) | (1.79-8.94) | ||
GM-CFC (104/kg) | ||||||
N | 5 | 18 | 5 | 7 | ||
Median | 5.01 | 20.43 | 40.21 | 47.93 | ||
Range | (0.10-49.64) | (0.13-223.76) | (18.7-123.07) | (9.11-121.00) | ||
BFU-E (104/kg) | ||||||
N | 5 | 18 | 5 | 7 | ||
Median | 8.90 | 36.87 | 64.92 | 122.71 | ||
Range | (0.36-21.28) | (0.00-601.46) | (12.50-131.55) | (35.82-283.00) |
Results from analysis of variance showed a statistically significant difference (P ≤ .01) between extensive and non–extensively treated patients for all mobilization parameters.
CD34+, GM-CFC, and BFU-E were log transformed.