Table 5.

Previous Chemotherapy, Impact on Mobilization Total Yields

Previous Chemotherapy/Treatment5-150
ExtensiveNonextensive
Filgrastim AloneAll CombinationsFilgrastim AloneAll Combinations
CD34+ (106/kg) 
18 
Median 0.28 1.76 3.68 5.27 
Range (0.03-3.39) (0.09-12.04) (2.95-20.68) (1.79-8.94) 
GM-CFC (104/kg) 
18 
Median 5.01 20.43 40.21 47.93 
Range (0.10-49.64) (0.13-223.76) (18.7-123.07) (9.11-121.00) 
BFU-E (104/kg) 
18 
Median 8.90 36.87 64.92 122.71 
Range (0.36-21.28) (0.00-601.46) (12.50-131.55) (35.82-283.00) 
Previous Chemotherapy/Treatment5-150
ExtensiveNonextensive
Filgrastim AloneAll CombinationsFilgrastim AloneAll Combinations
CD34+ (106/kg) 
18 
Median 0.28 1.76 3.68 5.27 
Range (0.03-3.39) (0.09-12.04) (2.95-20.68) (1.79-8.94) 
GM-CFC (104/kg) 
18 
Median 5.01 20.43 40.21 47.93 
Range (0.10-49.64) (0.13-223.76) (18.7-123.07) (9.11-121.00) 
BFU-E (104/kg) 
18 
Median 8.90 36.87 64.92 122.71 
Range (0.36-21.28) (0.00-601.46) (12.50-131.55) (35.82-283.00) 

Results from analysis of variance showed a statistically significant difference (P ≤ .01) between extensive and non–extensively treated patients for all mobilization parameters.

F5-150

CD34+, GM-CFC, and BFU-E were log transformed.

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