Non-HLA Restriction of NK-Cell Recognition for K562 Target Cells
| Targets . | Effectors . | E:T Ratio . | ||
|---|---|---|---|---|
| . | . | 50:1 . | 25:1 . | 12.5:1 . |
| HLA-DR1/1 | 67 ± 10 P > .05 | 57 ± 8 P > .5 | 49 ± 10 P > .5 | |
| K562 | HLA-DR2/2 | 61 ± 2 | 52 ± 7 | 41 ± 0 |
| HLA-DR1/1 | 41 ± 6 P > .1 | 32 ± 10 P > .5 | 26 ± 13 P > .1 | |
| K562DR1 | HLA-DR2/2 | 46 ± 7 | 30 ± 13 | 12 ± 10 |
| Targets . | Effectors . | E:T Ratio . | ||
|---|---|---|---|---|
| . | . | 50:1 . | 25:1 . | 12.5:1 . |
| HLA-DR1/1 | 67 ± 10 P > .05 | 57 ± 8 P > .5 | 49 ± 10 P > .5 | |
| K562 | HLA-DR2/2 | 61 ± 2 | 52 ± 7 | 41 ± 0 |
| HLA-DR1/1 | 41 ± 6 P > .1 | 32 ± 10 P > .5 | 26 ± 13 P > .1 | |
| K562DR1 | HLA-DR2/2 | 46 ± 7 | 30 ± 13 | 12 ± 10 |