Properties of HTLV-I–Infected Clones
| Clone . | Phenotype . | Spontaneous Proliferation (cpm) . | p24 (ng/mL) . | Syncytium Formation . | PBL Immortalization . | LTR-CAT Activity3-150 . |
|---|---|---|---|---|---|---|
| Du4 | CD4 | 8,172 | 8 | +++ | + | 10.3 |
| Du7 | CD8 | 15,525 | >28 | ND | ND | ND |
| Du26 | CD4 | 4,963 | 7 | − | − | 9.5 |
| Mu16 | CD4 | 6,912 | 10 | + | +++ | 13.3 |
| Du20 | CD4 | 218 | <0.02 | − | − | 0.65 |
| Du34 | CD4 | 182 | <0.02 | − | − | 0.74 |
| Du43 | CD4 | 148 | <0.02 | − | − | 0.51 |
| Mu40 | CD4 | 416 | <0.02 | − | ND | 0.36 |
| Ph1C | CD8 | 41 | <0.02 | − | ND | 0.45 |
| RM10 | ND | 180 | <0.02 | ND | ND | ND |
| CP9 | CD4 | 346 | <0.02 | ND | ND | ND |
| CP10 | CD4 | 198 | <0.02 | ND | ND | ND |
| Clone . | Phenotype . | Spontaneous Proliferation (cpm) . | p24 (ng/mL) . | Syncytium Formation . | PBL Immortalization . | LTR-CAT Activity3-150 . |
|---|---|---|---|---|---|---|
| Du4 | CD4 | 8,172 | 8 | +++ | + | 10.3 |
| Du7 | CD8 | 15,525 | >28 | ND | ND | ND |
| Du26 | CD4 | 4,963 | 7 | − | − | 9.5 |
| Mu16 | CD4 | 6,912 | 10 | + | +++ | 13.3 |
| Du20 | CD4 | 218 | <0.02 | − | − | 0.65 |
| Du34 | CD4 | 182 | <0.02 | − | − | 0.74 |
| Du43 | CD4 | 148 | <0.02 | − | − | 0.51 |
| Mu40 | CD4 | 416 | <0.02 | − | ND | 0.36 |
| Ph1C | CD8 | 41 | <0.02 | − | ND | 0.45 |
| RM10 | ND | 180 | <0.02 | ND | ND | ND |
| CP9 | CD4 | 346 | <0.02 | ND | ND | ND |
| CP10 | CD4 | 198 | <0.02 | ND | ND | ND |
Abbreviations: −, no syncytia; +, 10% to 30% of cells form syncytia; +++, >70% of cells form syncytia (on microscopic examination); ND, not done.
CAT activity expressed as percentage acetylation of 14C-chloramphenicol.