Sequential Adherence Studies on Patient A.M. Compared With Matched Controls
| Clinical Presentation . | Shear Force (dynes/cm2 ) . | Total No. of RBC Observed . | No. of Adherent RBC for A.M. . | No. of Adherent RBC Matched Control . | P . |
|---|---|---|---|---|---|
| Increased frequency of symptoms | 20 | 6,300 | 44 | 10 | <.0001 |
| over 6 mo of observation | 30 | 4,200 | 29 | 7 | .0002 |
| 55 | 2,100 | 12 | 3 | .02 | |
| Low dose pentox | 20 | 4,200 | 21 | 14 | .16 |
| over 2 yrs. no | 30 | 2,800 | 11 | 5 | .14 |
| acute crises | 55 | 1,400 | 5 | 3 | .36 |
| Pentox stopped on 2 occasions | 20 | 4,200 | 44 | 6 | <.0001 |
| and crises recurred | 30 | 2,800 | 22 | 2 | <.0001 |
| 55 | 1,400 | 11 | 1 | .003 |
| Clinical Presentation . | Shear Force (dynes/cm2 ) . | Total No. of RBC Observed . | No. of Adherent RBC for A.M. . | No. of Adherent RBC Matched Control . | P . |
|---|---|---|---|---|---|
| Increased frequency of symptoms | 20 | 6,300 | 44 | 10 | <.0001 |
| over 6 mo of observation | 30 | 4,200 | 29 | 7 | .0002 |
| 55 | 2,100 | 12 | 3 | .02 | |
| Low dose pentox | 20 | 4,200 | 21 | 14 | .16 |
| over 2 yrs. no | 30 | 2,800 | 11 | 5 | .14 |
| acute crises | 55 | 1,400 | 5 | 3 | .36 |
| Pentox stopped on 2 occasions | 20 | 4,200 | 44 | 6 | <.0001 |
| and crises recurred | 30 | 2,800 | 22 | 2 | <.0001 |
| 55 | 1,400 | 11 | 1 | .003 |