Table 1. Characterization of Patients... | American Society of Hematology

Table 1.

Characterization of Patients With HCV-Associated Cryoglobulinemia Who Had Complete or Minor Responses to Interferon-α Therapy

Variable	Complete Responders	Minor Responders	P Value
	n = 17	n = 14
Age (yr)^*	57.7 ± 7.5	51.7 ± 10.2	.064
Sex (F/M)	9/8	10/5	NS
Duration of disease (yr)^*	8.4 ± 4.5	8.4 ± 4.2	NS
Previous therapies (no. of patients):
Steroids	15	13	NS
Cyclophosphamide	9	9	NS
Total follow-up (mo)^*	52.5 ± 35.7	76.6 ± 24.7	NS
Liver disease (no. of patients)	10	8	NS
Initial cryocrit (%)^*	14.9 ± 12.4	24.9 ± 18	.069
IgM level (mg/dL)^*	338 ± 158	428 ± 247	.22
Solitary anti-C22 (no. of patients)	8	1	.02
Viremia^*	7.9 ± 5.4^†	47 ± 26^†	.04
Genotype (no./23 patients tested)
1a	4	0	.10
1b	5	6	NS
2b	4	4	NS

Variable	Complete Responders	Minor Responders	P Value
	n = 17	n = 14
Age (yr)^*	57.7 ± 7.5	51.7 ± 10.2	.064
Sex (F/M)	9/8	10/5	NS
Duration of disease (yr)^*	8.4 ± 4.5	8.4 ± 4.2	NS
Previous therapies (no. of patients):
Steroids	15	13	NS
Cyclophosphamide	9	9	NS
Total follow-up (mo)^*	52.5 ± 35.7	76.6 ± 24.7	NS
Liver disease (no. of patients)	10	8	NS
Initial cryocrit (%)^*	14.9 ± 12.4	24.9 ± 18	.069
IgM level (mg/dL)^*	338 ± 158	428 ± 247	.22
Solitary anti-C22 (no. of patients)	8	1	.02
Viremia^*	7.9 ± 5.4^†	47 ± 26^†	.04
Genotype (no./23 patients tested)
1a	4	0	.10
1b	5	6	NS
2b	4	4	NS

Abbreviation: NS, not significant.

Mean ± 1 standard deviation.

HCV copies/mL × 10⁶. Results from four patients tested in each group.