MPO Activity of Neutrophils From MPO-Deficient Subject and Her Family Members
| . | Guaiacolic Units/106 Cells % Control . |
|---|---|
| Control subjects | 100 |
| MPO-deficient subject (MP) | 7 |
| Mother (VP) | 24 |
| Father (DP) | 3 |
| . | Guaiacolic Units/106 Cells % Control . |
|---|---|
| Control subjects | 100 |
| MPO-deficient subject (MP) | 7 |
| Mother (VP) | 24 |
| Father (DP) | 3 |
Granulocyte suspensions containing 95% to 97% neutrophils were diluted in sample buffer and guaiacol oxidation was monitored following the OD470 increase at 37°C for 1 minute.25 Peroxidase activity of control subjects was 103 ± 9 SD (n = 6) Guaiacolic Units/106 cellule.