Table 2. Expression of PML and PML/RARα... | American Society of Hematology

Table 2.

Expression of PML and PML/RARα Proteins in 92 ANLL

Immunocytochemical Pattern of PG-M3^*	Total	RT-PCR	Proposed Morphologic Diagnosis (FAB)
		(PML/RARα)
PML wild-type (speckled)	78	0/51^†	72 non-APL,‡ 6 APL
PML/RARα (microgranular)	14	14/14	11 APL, 3 non-APLρ

Immunocytochemical Pattern of PG-M3^*	Total	RT-PCR	Proposed Morphologic Diagnosis (FAB)
		(PML/RARα)
PML wild-type (speckled)	78	0/51^†	72 non-APL,‡ 6 APL
PML/RARα (microgranular)	14	14/14	11 APL, 3 non-APLρ

Blindly evaluated in cytospins and/or smears by three different observers (see Materials and Methods).

Including the 6 cases misdiagnosed as APL.

M0 (n = 1); M1 (n = 3); M2 (n = 28); M4 (n = 23); M4Eo (n = 3); M5 (n = 11), M6 (n = 2); M7 (n = 1).

ρ M4 (n = 2), M5b (n = 1).