Table 3. Diseases States and Conditions... | American Society of Hematology

Table 3.

Diseases States and Conditions Associated With Contact System Activation

Disease^3-150	PK		HK		C1 INH		XI (Act.)	XII (Act.)	α2M-Kal Complexes (Ant.)	C1 INH-Kal Complexes (Ant.)
	Act.	Ant.	Act.	Ant.	Act.	Ant.
HAE^14,259	D	D	D	D	D	D	—	—	I	—
Sepsis270 276	D	—	—	—	D	—	—	D	I	—
Typhoid fever272	D	U	—	—	D	I	—	—	—	—
ARDS269	D	D	D	U	D	I	U	D	—	—
RMSF274	D	D	—	—	I	—	I	U	—	I
Low-dose endotoxin277	D	U	D	—	—	—	D	—	I	—
CPB^281-283	—	—	—	—	—	—	—	—	—	I

Disease^3-150	PK		HK		C1 INH		XI (Act.)	XII (Act.)	α2M-Kal Complexes (Ant.)	C1 INH-Kal Complexes (Ant.)
	Act.	Ant.	Act.	Ant.	Act.	Ant.
HAE^14,259	D	D	D	D	D	D	—	—	I	—
Sepsis270 276	D	—	—	—	D	—	—	D	I	—
Typhoid fever272	D	U	—	—	D	I	—	—	—	—
ARDS269	D	D	D	U	D	I	U	D	—	—
RMSF274	D	D	—	—	I	—	I	U	—	I
Low-dose endotoxin277	D	U	D	—	—	—	D	—	I	—
CPB^281-283	—	—	—	—	—	—	—	—	—	I

Abbreviations: D, decreased; U, unaffected; I, increased.

F3-150

The following diseases were investigated: HAE, hereditary angiodema; ARDS, adult respiratory distress syndrome; RMSF, Rocky Mountain spotted fever; CPB, cardiopulmonary bypass. The numbers after the disease category are references.

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