Characteristics of 19 Patients With Mantle Cell Lymphoma in Whom a Molecular Marker Was Identified
| UPN# . | Age . | Sex . | Stage at Presentation . | BM Involvement . | MoAbs Used for Purging . | CR in History . | PCR Amplification . | |||
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | . | At Diagnosis . | At BMT . | . | . | BCL-1/IgH . | BCL-2/IgH . | ASO Primer . |
| 1049 | 58 | M | IIB | 0% | 0% | B1 | No | Pos | Neg | Yes |
| 1249 | 34 | F | IVB | 10% | 10% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1483 | 41 | F | IIIB | 30% | 5%-10% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1508 | 54 | M | IIIB | 0% | 0% | B1, B5, J5 | No | Pos | Neg | No |
| 1653 | 38 | F | IVB | <5% | <5% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1676 | 41 | M | IVB | 5% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1698 | 55 | M | IVB | 60%-70% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1705 | 38 | M | IVB | 5%-10% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1751 | 43 | M | IVA | 40% | 5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1826 | 46 | M | IVB | 20% | <5% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1846 | 52 | M | IIIA | 0% | 0% | B1, B4, B5, J5 | Yes | Pos | Neg | No |
| 1863 | 43 | M | IVB | 70% | <5% | B1, B5, J5 | No | Neg | Neg | Yes |
| 1910 | 50 | M | IVA | <5% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1917 | 58 | M | IVB | 20%-25% | 0% | B1, B4, B5, J5 | Yes | Pos | Neg | No |
| 1946 | 53 | M | IVA | 80% | 0% | B1, B5, J5 | No | Neg | Neg | Yes |
| 1972 | 42 | M | IVB | 5% | 10% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1992 | 40 | M | IVB | 5% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| Syn | 44 | M | IVA | 50% | 10% | No | Neg | Neg | Yes | |
| Allo | 58 | M | IVB | 50%-60% | 10% | T12 | No | Pos | Neg | Yes |
| UPN# . | Age . | Sex . | Stage at Presentation . | BM Involvement . | MoAbs Used for Purging . | CR in History . | PCR Amplification . | |||
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | . | At Diagnosis . | At BMT . | . | . | BCL-1/IgH . | BCL-2/IgH . | ASO Primer . |
| 1049 | 58 | M | IIB | 0% | 0% | B1 | No | Pos | Neg | Yes |
| 1249 | 34 | F | IVB | 10% | 10% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1483 | 41 | F | IIIB | 30% | 5%-10% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1508 | 54 | M | IIIB | 0% | 0% | B1, B5, J5 | No | Pos | Neg | No |
| 1653 | 38 | F | IVB | <5% | <5% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1676 | 41 | M | IVB | 5% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1698 | 55 | M | IVB | 60%-70% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1705 | 38 | M | IVB | 5%-10% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1751 | 43 | M | IVA | 40% | 5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1826 | 46 | M | IVB | 20% | <5% | B1, B5, J5 | No | Pos | Neg | Yes |
| 1846 | 52 | M | IIIA | 0% | 0% | B1, B4, B5, J5 | Yes | Pos | Neg | No |
| 1863 | 43 | M | IVB | 70% | <5% | B1, B5, J5 | No | Neg | Neg | Yes |
| 1910 | 50 | M | IVA | <5% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1917 | 58 | M | IVB | 20%-25% | 0% | B1, B4, B5, J5 | Yes | Pos | Neg | No |
| 1946 | 53 | M | IVA | 80% | 0% | B1, B5, J5 | No | Neg | Neg | Yes |
| 1972 | 42 | M | IVB | 5% | 10% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| 1992 | 40 | M | IVB | 5% | <5% | B1, B4, B5, J5 | No | Neg | Neg | Yes |
| Syn | 44 | M | IVA | 50% | 10% | No | Neg | Neg | Yes | |
| Allo | 58 | M | IVB | 50%-60% | 10% | T12 | No | Pos | Neg | Yes |
Abbreviations: UPN #, unique patient number; BM, bone marrow; BMT, bone marrow transplantation; CR, complete remission; ASO, allele specific oligonucleotide; syn, syngeneic BMT; allo, allogeneic BMT.