Relative Frequency (%) of Complications During Induction Cycle I
. | Control Group . | GM-CSF . |
---|---|---|
. | . | Group . |
Hemorrhage | ||
Only petechiae | 21 | 26 |
Other bleedings | 26 | 25 |
Liver | ||
Mild-moderate (1.25-5 × normal) | 31 | 37 |
Severe (≥5 × normal) | 11 | 10 |
Oral | ||
Erythema | 17 | 14 |
Ulcers and other toxicity | 7 | 12 |
Nausea/vomiting | 30/35 | 32/34 |
Diarrhea4-150 | ||
Less than 2 days | 23 | 23 |
More severe | 18 | 30 |
Renal4-150 | ||
Mild-moderate (1.26-5 × normal) | 21 | 31 |
Severe (≥5 × normal) | 3 | 3 |
Fever4-150 | ||
Subfebrile (<38°C) | 12 | 11 |
≥38°C | 71 | 81 |
Cutaneous4-150 | ||
Erythema/desquamation/papules etc | 43 | 55 |
Cardiac rhythm | 22 | 22 |
Neurotoxicity | 11 | 12 |
Bone pain | 6 | 8 |
Hypotension4-151 | 13 | 26 |
Fluid retention‡ | 56 | 71 |
Chills‡ | 18 | 37 |
Phlebitis4-150 | 8 | 17 |
Infection | 77 | 78 |
. | Control Group . | GM-CSF . |
---|---|---|
. | . | Group . |
Hemorrhage | ||
Only petechiae | 21 | 26 |
Other bleedings | 26 | 25 |
Liver | ||
Mild-moderate (1.25-5 × normal) | 31 | 37 |
Severe (≥5 × normal) | 11 | 10 |
Oral | ||
Erythema | 17 | 14 |
Ulcers and other toxicity | 7 | 12 |
Nausea/vomiting | 30/35 | 32/34 |
Diarrhea4-150 | ||
Less than 2 days | 23 | 23 |
More severe | 18 | 30 |
Renal4-150 | ||
Mild-moderate (1.26-5 × normal) | 21 | 31 |
Severe (≥5 × normal) | 3 | 3 |
Fever4-150 | ||
Subfebrile (<38°C) | 12 | 11 |
≥38°C | 71 | 81 |
Cutaneous4-150 | ||
Erythema/desquamation/papules etc | 43 | 55 |
Cardiac rhythm | 22 | 22 |
Neurotoxicity | 11 | 12 |
Bone pain | 6 | 8 |
Hypotension4-151 | 13 | 26 |
Fluid retention‡ | 56 | 71 |
Chills‡ | 18 | 37 |
Phlebitis4-150 | 8 | 17 |
Infection | 77 | 78 |