Spi-1 Rearrangement and p53 Alterations in Leukemic Cell Lines
| Leukemic Cell Line . | Spi-1 Rearrangement . | p53 Alterations . | ||
|---|---|---|---|---|
| . | . | Base Change . | Codon . | Amino Acid Change . |
| Control-A | − | G → A | 170 | Val → Met |
| Control-B | + | |||
| Control-C | − | |||
| Control-D | + | G → T | 271 | Arg → Leu |
| Control-E | + | |||
| Control-F | + | |||
| Control-G | − | Deletion or disruption | ||
| Control-H | + | Deletion or disruption | ||
| Control-I | + | A → G | 213 | Ser → Gly |
| Control-J | − | |||
| Folate deficient 1 A | − | A → G | 278 | Arg → Gly |
| Folate deficient 1 B | + | C deletion | 311 | Frame shift |
| Folate deficient 1 C | + | T → G | 275 | Cys → Gly |
| Folate deficient 1 D | + | T → G | 275 | Cys → Gly |
| Folate deficient 1 E | + | G → A | 246 | Arg → His |
| Folate deficient 1 F | − | |||
| Folate deficient 1 G | + | G → A | 173 | Cys → Tyr |
| Folate deficient 1 H | + | |||
| Folate deficient 1 I | + | Deletion or disruption | ||
| Folate deficient 1 J | + | T → C | 108 | Leu → Pro |
| Folate deficient 1 K | + | Deletion or disruption | ||
| Folate deficient 1 L | + | |||
| Folate deficient 1 M | + | G → A | 256 | Glu → Lys |
| Folate deficient 1 N | − | C → T | 276 | Pro → Ser |
| Folate deficient 1 O | + | |||
| Folate deficient 1 P | + | |||
| Folate deficient 2 A | + | |||
| Folate deficient 2 B | − | T → A | 232 | Tyr → Asn |
| Folate deficient 2 C | − | |||
| Folate deficient 2 D | + | T → G | 275 | Cys → Gly |
| Folate deficient 2 E | + | A → C | 266 | Asp → Ala |
| Folate deficient 2 F | + | |||
| Folate deficient 2 G | − | Deletion or disruption | ||
| Folate deficient 2 H | + | |||
| Folate deficient 2 I | − | A → G | 152 | Ser → Gly |
| Leukemic Cell Line . | Spi-1 Rearrangement . | p53 Alterations . | ||
|---|---|---|---|---|
| . | . | Base Change . | Codon . | Amino Acid Change . |
| Control-A | − | G → A | 170 | Val → Met |
| Control-B | + | |||
| Control-C | − | |||
| Control-D | + | G → T | 271 | Arg → Leu |
| Control-E | + | |||
| Control-F | + | |||
| Control-G | − | Deletion or disruption | ||
| Control-H | + | Deletion or disruption | ||
| Control-I | + | A → G | 213 | Ser → Gly |
| Control-J | − | |||
| Folate deficient 1 A | − | A → G | 278 | Arg → Gly |
| Folate deficient 1 B | + | C deletion | 311 | Frame shift |
| Folate deficient 1 C | + | T → G | 275 | Cys → Gly |
| Folate deficient 1 D | + | T → G | 275 | Cys → Gly |
| Folate deficient 1 E | + | G → A | 246 | Arg → His |
| Folate deficient 1 F | − | |||
| Folate deficient 1 G | + | G → A | 173 | Cys → Tyr |
| Folate deficient 1 H | + | |||
| Folate deficient 1 I | + | Deletion or disruption | ||
| Folate deficient 1 J | + | T → C | 108 | Leu → Pro |
| Folate deficient 1 K | + | Deletion or disruption | ||
| Folate deficient 1 L | + | |||
| Folate deficient 1 M | + | G → A | 256 | Glu → Lys |
| Folate deficient 1 N | − | C → T | 276 | Pro → Ser |
| Folate deficient 1 O | + | |||
| Folate deficient 1 P | + | |||
| Folate deficient 2 A | + | |||
| Folate deficient 2 B | − | T → A | 232 | Tyr → Asn |
| Folate deficient 2 C | − | |||
| Folate deficient 2 D | + | T → G | 275 | Cys → Gly |
| Folate deficient 2 E | + | A → C | 266 | Asp → Ala |
| Folate deficient 2 F | + | |||
| Folate deficient 2 G | − | Deletion or disruption | ||
| Folate deficient 2 H | + | |||
| Folate deficient 2 I | − | A → G | 152 | Ser → Gly |