Table 1.

Patient Characteristics

Autologous (%)Unrelated (%)P
Total 214  337   
Sex 
Male 142 (66) 203 (60) .15 
Female 72 (34) 134 (40)  
Age 
0-18 yrs 160 (75) 216 (64) .009 
19+ yrs 54 (25) 121 (36)  
Remission No. 
1* 51 (23.8) 52 (15.6) <.001 
 [18% ≤ 18; 6% > 18] [9% ≤ 18; 7% > 18]  
98 (45.8) 106 (31.7)  
 [35% ≤ 18; 11% > 18] [24% ≤ 18; 7% > 18]  
3+ 53 (24.8) [18% ≤ 18; 7% > 18] 93 (27.8) [21% ≤ 18; 7% > 18]  
Relapse 12 (5.6) 83 (24.9)  
 [5% ≤ 18; 1% > 18] [10% ≤ 18; 14% > 18]  
Year of BMT 
1987-1990 142 (66.4) 94 (27.9) <.001 
1991-1993 72 (33.6) 243 (72.1)  
Conditioning Regimen 
Cy + TBI 37 (17.3) 125 (37) <.001 
Cy + TBI + other drugs 170 (79.4) 183 (54)  
Chemotherapy without TBI 7 (3.3) 29 (9) 
Autologous (%)Unrelated (%)P
Total 214  337   
Sex 
Male 142 (66) 203 (60) .15 
Female 72 (34) 134 (40)  
Age 
0-18 yrs 160 (75) 216 (64) .009 
19+ yrs 54 (25) 121 (36)  
Remission No. 
1* 51 (23.8) 52 (15.6) <.001 
 [18% ≤ 18; 6% > 18] [9% ≤ 18; 7% > 18]  
98 (45.8) 106 (31.7)  
 [35% ≤ 18; 11% > 18] [24% ≤ 18; 7% > 18]  
3+ 53 (24.8) [18% ≤ 18; 7% > 18] 93 (27.8) [21% ≤ 18; 7% > 18]  
Relapse 12 (5.6) 83 (24.9)  
 [5% ≤ 18; 1% > 18] [10% ≤ 18; 14% > 18]  
Year of BMT 
1987-1990 142 (66.4) 94 (27.9) <.001 
1991-1993 72 (33.6) 243 (72.1)  
Conditioning Regimen 
Cy + TBI 37 (17.3) 125 (37) <.001 
Cy + TBI + other drugs 170 (79.4) 183 (54)  
Chemotherapy without TBI 7 (3.3) 29 (9) 

Abbreviations: Cy, Cyclophosphamide; TBI, total body irradiation; BMT, bone marrow transplantation; URD, unrelated donor marrow.

*

Percent shown in brackets for children ≤18; adults >18.

Includes BMT in relapse and primary induction failure (autologous 0; URD 3).

χ 2 analysis; TBI v no TBI; P = .02.

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