Outcomes After BMT for ALL: Univariate Analysis
| (n) . | Relapse . | Transplant-Related Mortality . | Disease-Free Survival . | |||
|---|---|---|---|---|---|---|
| . | (% ± 95% CI) . | P . | (% ± 95% CI) . | P . | (% ± 95% CI) . | P . |
| CR1 | ||||||
| Auto (51) | 53 ± 16% | .12 | 19 ± 15% | .0001 | 42 ± 15% | .03 |
| URD (52) | 33 ± 23% | 57 ± 14% | 32 ± 14% | |||
| CR2 | ||||||
| Auto (98) | 76 ± 10% | .0001 | 14 ± 9% | .0001 | 20 ± 9% | .02 |
| URD (106) | 17 ± 9% | 48 ± 12% | 42 ± 11% | |||
| CR3 | ||||||
| Auto (40) | 74 ± 20% | .05 | 21 ± 13% | .04 | 19 ± 16% | .85 |
| URD (79) | 47 ± 16% | 58 ± 13% | 23 ± 10% | |||
| CR4+ | ||||||
| Auto (13) | 60 ± 31% | .29 | 23 ± 23% | .02 | 31 ± 25% | .30 |
| URD (14) | 73 ± 45% | 10% | 0 | |||
| In relapse | ||||||
| Auto (12) | 90 ± 19% | .0001 | 27 ± 27% | .37 | 0 | .10 |
| URD (83) | 60 ± 16% | 63 ± 13% | 16 ± 8% | |||
| (n) . | Relapse . | Transplant-Related Mortality . | Disease-Free Survival . | |||
|---|---|---|---|---|---|---|
| . | (% ± 95% CI) . | P . | (% ± 95% CI) . | P . | (% ± 95% CI) . | P . |
| CR1 | ||||||
| Auto (51) | 53 ± 16% | .12 | 19 ± 15% | .0001 | 42 ± 15% | .03 |
| URD (52) | 33 ± 23% | 57 ± 14% | 32 ± 14% | |||
| CR2 | ||||||
| Auto (98) | 76 ± 10% | .0001 | 14 ± 9% | .0001 | 20 ± 9% | .02 |
| URD (106) | 17 ± 9% | 48 ± 12% | 42 ± 11% | |||
| CR3 | ||||||
| Auto (40) | 74 ± 20% | .05 | 21 ± 13% | .04 | 19 ± 16% | .85 |
| URD (79) | 47 ± 16% | 58 ± 13% | 23 ± 10% | |||
| CR4+ | ||||||
| Auto (13) | 60 ± 31% | .29 | 23 ± 23% | .02 | 31 ± 25% | .30 |
| URD (14) | 73 ± 45% | 10% | 0 | |||
| In relapse | ||||||
| Auto (12) | 90 ± 19% | .0001 | 27 ± 27% | .37 | 0 | .10 |
| URD (83) | 60 ± 16% | 63 ± 13% | 16 ± 8% | |||
Shown are Kaplan-Meier estimates ± 95% confidence limits within each cohort divided by remission number and type of transplant. P values represent log-rank univariate comparisons.
Abbreviations: BMT, bone marrow transplantation; ALL, acute lymphoblastic leukemia; CI, confidence interval; Auto, autologous; URD, unrelated donor marrow.