Time-Course Experiments
| Time (min) . | HR2/HR2 . | 506RR . | 506RQ . |
|---|---|---|---|
| 0 | 100 | 100 | 100 |
| 30 | 95 ± 4 | 95 ± 8 | 94 ± 6 |
| 60 | 81 ± 9 | 81 ± 16 | 75 ± 18 |
| 90 | 79 ± 4 | 78 ± 10 | 77 ± 19 |
| 120 | 76 ± 6 | 78 ± 13 | 72 ± 18 |
| 150 | 69 ± 2 | 66 ± 12 | 61 ± 12 |
| 180 | 61 ± 3 | 58 ± 19 | 49 ± 16 |
| 240 | 44 ± 5 | 493-150 | 383-150 |
| 300 | 35 ± 6 | 443-150 | 313-150 |
| Time (min) . | HR2/HR2 . | 506RR . | 506RQ . |
|---|---|---|---|
| 0 | 100 | 100 | 100 |
| 30 | 95 ± 4 | 95 ± 8 | 94 ± 6 |
| 60 | 81 ± 9 | 81 ± 16 | 75 ± 18 |
| 90 | 79 ± 4 | 78 ± 10 | 77 ± 19 |
| 120 | 76 ± 6 | 78 ± 13 | 72 ± 18 |
| 150 | 69 ± 2 | 66 ± 12 | 61 ± 12 |
| 180 | 61 ± 3 | 58 ± 19 | 49 ± 16 |
| 240 | 44 ± 5 | 493-150 | 383-150 |
| 300 | 35 ± 6 | 443-150 | 313-150 |
Genotypes of patients (HR2/HR2 and 506RQ) and of a normal control (506RR) are indicated. The mean percentage of basal activity at time zero is reported. Three determinations were performed, unless otherwise indicated.
Mean of only two values.