Drug-Resistance Profile (combined data for prednisolone, L-asparaginase, and vincristine) and the Occurrence of Leukemia-Related Events: No CR, Relapse
| . | Most Sensitive ↔ Most Resistant . | ||||||
|---|---|---|---|---|---|---|---|
| . | . | . | . | . | . | . | . |
| Score* . | |||||||
| . | . | ||||||
| . | 3 . | 4 . | 5 . | 6 . | 7 . | 8 . | 9 . |
| No. of patients | 5 | 18 | 20 | 27 | 23 | 13 | 12 |
| Event | 0 | 0 | 4 | 6 | 14 | 6 | 6 |
| Event-rate (%) | 0 | 0 | 20 | 22 | 61 | 46 | 50 |
| . | Most Sensitive ↔ Most Resistant . | ||||||
|---|---|---|---|---|---|---|---|
| . | . | . | . | . | . | . | . |
| Score* . | |||||||
| . | . | ||||||
| . | 3 . | 4 . | 5 . | 6 . | 7 . | 8 . | 9 . |
| No. of patients | 5 | 18 | 20 | 27 | 23 | 13 | 12 |
| Event | 0 | 0 | 4 | 6 | 14 | 6 | 6 |
| Event-rate (%) | 0 | 0 | 20 | 22 | 61 | 46 | 50 |
For each drug a ‘sensitive’ LC50 was counted as 1, an ‘intermediate’ LC50 as 2, and a ‘resistant’ LC50 as 3. Combining these counts results in a total score from 3 to 9.