Table 5. Multivariate Risk Group... | American Society of Hematology

Table 5.

Multivariate Risk Group Stratified Analysis of the Predictive Value of Potentially Prognostic Factors of Leukemia-Related Events in 152 Children With Initial ALL

Factor	Relative Risk	P Value Multivariate^5-151
	(95% C.I.)^5-150

Age
<2 or ≥10 yr v 2-9 yr	0.7 (0.3-1.5)	.33
BFM risk factor^5-152
≥1.20 v <1.20	1.8 (0.8-4.0)	.16
Immunophenotype
Pro-B or T-cell v common or pre-B	2.5 (0.9-7.0)	.09
DNA ploidy
Nonhyperdiploid v hyperdiploid	1.0 (0.2-4.8)	.97
Drug-resistance profile
Resistant (score ≥7) v sensitive (score <7)	7.0 (2.9-16.5)	<.001

Factor	Relative Risk	P Value Multivariate^5-151
	(95% C.I.)^5-150

Age
<2 or ≥10 yr v 2-9 yr	0.7 (0.3-1.5)	.33
BFM risk factor^5-152
≥1.20 v <1.20	1.8 (0.8-4.0)	.16
Immunophenotype
Pro-B or T-cell v common or pre-B	2.5 (0.9-7.0)	.09
DNA ploidy
Nonhyperdiploid v hyperdiploid	1.0 (0.2-4.8)	.97
Drug-resistance profile
Resistant (score ≥7) v sensitive (score <7)	7.0 (2.9-16.5)	<.001

F5-150

95%-Confidence interval.

F5-151

Using a model including all factors mentioned.

F5-152

Based on peripheral leukemic cell count, and liver and spleen size.35

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