Production of IL-8 by Human Monocytes Upon Stimulation by IL-15
| Treatment* . | IL-8 (ng/mL) Mean (SD) . | |
|---|---|---|
| . | 6 h . | 24 h . |
| Medium | 14 (3.3) | 27 (4.1) |
| IL-15 (10 ng/mL) | 25 (1.8) | 42 (3.4) |
| (100 ng/mL) | 34† (2.6) | 70† (6.2) |
| (1,000 ng/mL) | 141† (6.4) | 176† (8.7) |
| Treatment* . | IL-8 (ng/mL) Mean (SD) . | |
|---|---|---|
| . | 6 h . | 24 h . |
| Medium | 14 (3.3) | 27 (4.1) |
| IL-15 (10 ng/mL) | 25 (1.8) | 42 (3.4) |
| (100 ng/mL) | 34† (2.6) | 70† (6.2) |
| (1,000 ng/mL) | 141† (6.4) | 176† (8.7) |
Supernatants derived from monocytes cultured with increasing concentrations of IL-15 (from 10 to 1,000 ng/mL), or medium alone for 6 or 24 hours were analyzed in duplicate for their concentration of IL-8 by ELISA. Results shown are representative of a single experiment out of three performed.
Significant production in comparison to medium (P < .05).