Table 1.

AML Patients Whose Blood or Marrow Samples Were Studied in LTC

Patient SampleAge (yr)SexFAB TypeWBC (% blasts)*Bone Marrow CytogeneticsFISH Probe†
(×109/L)[% abnormal]
1 68 M RAEBIT 27 (14) 45,X,−Y,inv(16)(p13q22) [92] Y, 8 
2 44 M M1 165 (95) 45,X,−Y,t(8; 21)(q22q22) [100] Y, 8 
3 64 F M5A 129 (95) 47,XX,+8,rea(11)(q23) [100] 8 
4 69 F M4 65 (83) 47,XX,+8 [100] 8 
5 59 F M5A 36 (94) 47,XX,−7,+8,+8,t(9; 11)(p22q23) [100] 8 
6 69 F M5B 155 (95) 46,XX,t(9; 11)(p22q23) [100] 11q23 
7 77 M M2 57 (51) 47,XY,+8,t(12; 22)(p13q12)del(20)(q1.2q1.3) [100] 8 
8 36 F M4Eo 18 (42) 47,XX,inv(16)(p13q22),+22 [87] 16p13 
9 55 M M5 106 (95) 46,XY; 48,XY,+8+8 [58] 8 
10 48 F M4Eo 18 (52) 46,XX,inv(16)(p13q22) [100] 16p13 
Patient SampleAge (yr)SexFAB TypeWBC (% blasts)*Bone Marrow CytogeneticsFISH Probe†
(×109/L)[% abnormal]
1 68 M RAEBIT 27 (14) 45,X,−Y,inv(16)(p13q22) [92] Y, 8 
2 44 M M1 165 (95) 45,X,−Y,t(8; 21)(q22q22) [100] Y, 8 
3 64 F M5A 129 (95) 47,XX,+8,rea(11)(q23) [100] 8 
4 69 F M4 65 (83) 47,XX,+8 [100] 8 
5 59 F M5A 36 (94) 47,XX,−7,+8,+8,t(9; 11)(p22q23) [100] 8 
6 69 F M5B 155 (95) 46,XX,t(9; 11)(p22q23) [100] 11q23 
7 77 M M2 57 (51) 47,XY,+8,t(12; 22)(p13q12)del(20)(q1.2q1.3) [100] 8 
8 36 F M4Eo 18 (42) 47,XX,inv(16)(p13q22),+22 [87] 16p13 
9 55 M M5 106 (95) 46,XY; 48,XY,+8+8 [58] 8 
10 48 F M4Eo 18 (52) 46,XX,inv(16)(p13q22) [100] 16p13 

Abbreviation: RAEBIT, refractory anemia with excess blasts in transformation.

*

WBC, peripheral blood total white blood cell count at diagnosis.

†

Probes used are described in detail in Materials and Methods.

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