Table 2.

Sodium/Lithium Countertransport Activity in Red Blood Cells

SubjectsZero time*Na+-freeNa+-richSLCmM[Li+]i
Control 0.025 0.380 0.584 0.204 
(n = 10) (0.014-0.048) (0.240-0.536) (0.440-0.741) (0.120-0.257) (7.5-9.5) 
II.1 (band 3 ↓) 0.093 2.202 2.851 0.649 11.3 
II.2 (band 3 ↓) 0.095 2.052 3.307 1.255 12.3 
3 (band 3 ↓) 0.084 1.327 2.043 0.716 11.6 
4 (band 3 ↓) 0.027 0.677 0.892 0.215 9.05 
5 (ankyrin ↓) 0.028 0.547 0.687 0.140 8.8 
SubjectsZero time*Na+-freeNa+-richSLCmM[Li+]i
Control 0.025 0.380 0.584 0.204 
(n = 10) (0.014-0.048) (0.240-0.536) (0.440-0.741) (0.120-0.257) (7.5-9.5) 
II.1 (band 3 ↓) 0.093 2.202 2.851 0.649 11.3 
II.2 (band 3 ↓) 0.095 2.052 3.307 1.255 12.3 
3 (band 3 ↓) 0.084 1.327 2.043 0.716 11.6 
4 (band 3 ↓) 0.027 0.677 0.892 0.215 9.05 
5 (ankyrin ↓) 0.028 0.547 0.687 0.140 8.8 
*

Lithium efflux to sodium-free medium at zero time at 0°C, in mmol 1,000 mL cells−1.

Efflux in mmol Li+ h−1 1,000 mL cells−1 SLC normal values: <0.41 mmol Li+ h−1 1,000 mL cells−1.

Mean values of 10 normal subjects, SD of the method: ±9.2%.

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