Effect of MoAb 2PH1 on Leukocyte Rolling in Venules of the Exposed Mouse Cremaster Muscle
| Treatment . | None . | |||
|---|---|---|---|---|
| . | 2PH1 . | RB40.34 . | ||
| . | 1 mg/kg . | 2 mg/kg . | 1 mg/kg . | |
| Wall shear rate (s−1) | 858 ± 81 | 823 ± 161 | 869 ± 202 | 638 ± 182 |
| Flow velocity (mm/s) | 2.0 ± 0.2 | 1.8 ± 0.3 | 2.5 ± 0.5 | 1.7 ± 0.5 |
| Diameter (μm) | 25.6 ± 1.0 | 24.0 ± 1.5 | 31.5 ± 1.8 | 27.4 ± 2.4 |
| WBC (cells/μL) | 5,990 ± 466 | 3,667 ± 256 | 3,086 ± 197 | 3,245 ± 202 |
| Rolling flux (cells/s) | 1.77 ± 0.20 | 0.79 ± 0.14 | 0.33 ± 0.05 | 0.01 ± 0.01 |
| Rolling flux (%) | 57.85 ± 7.02 | 48.35 ± 7.85 | 11.98 ± 3.31 | 0.41 ± 0.11 |
| Treatment . | None . | |||
|---|---|---|---|---|
| . | 2PH1 . | RB40.34 . | ||
| . | 1 mg/kg . | 2 mg/kg . | 1 mg/kg . | |
| Wall shear rate (s−1) | 858 ± 81 | 823 ± 161 | 869 ± 202 | 638 ± 182 |
| Flow velocity (mm/s) | 2.0 ± 0.2 | 1.8 ± 0.3 | 2.5 ± 0.5 | 1.7 ± 0.5 |
| Diameter (μm) | 25.6 ± 1.0 | 24.0 ± 1.5 | 31.5 ± 1.8 | 27.4 ± 2.4 |
| WBC (cells/μL) | 5,990 ± 466 | 3,667 ± 256 | 3,086 ± 197 | 3,245 ± 202 |
| Rolling flux (cells/s) | 1.77 ± 0.20 | 0.79 ± 0.14 | 0.33 ± 0.05 | 0.01 ± 0.01 |
| Rolling flux (%) | 57.85 ± 7.02 | 48.35 ± 7.85 | 11.98 ± 3.31 | 0.41 ± 0.11 |