Table 1. Clinical and Laboratory Data of... | American Society of Hematology

Table 1.

Clinical and Laboratory Data of Neutropenic Patients With and Without Infections

	No Infections (n = 51)	Infections (n = 15)	TwoSided P Value
Male:female	20:31	3:12	NS^*
Age	53 (range: 18-88)	61 (31-82)	NS
ANC (cells/μL)^-151	1,170 ± 320^-152	860 ± 477	.03
Range (cells/μL)	600-1,500	50-1,500
Plasma sFcγRIII (AU)	109 ± 66	49 ± 26	<.0001
Range (AU)	23-315	11-95
Bone marrow data
Not available	19 (37%)	4 (25%)
Normal marrow	25 (49%)	5 (31%)
Decreased myelopoiesis	2 (4%)	1 (6%)
Increased myelopoiesis	2 (4%)	2 (13%)
Possible dysplasia	2 (4%)	2 (13%)
Lymphocytosis	1 (2%)	1 (6%)
FcγR genotype^-153
FcγRIIA-131R	0.59	0.61
FcγRIIA-131H	0.41	0.39	NS
FcγRIIIB-NA1	0.29	0.32
FcγRIIIB-NA2	0.71	0.68	NS

	No Infections (n = 51)	Infections (n = 15)	TwoSided P Value
Male:female	20:31	3:12	NS^*
Age	53 (range: 18-88)	61 (31-82)	NS
ANC (cells/μL)^-151	1,170 ± 320^-152	860 ± 477	.03
Range (cells/μL)	600-1,500	50-1,500
Plasma sFcγRIII (AU)	109 ± 66	49 ± 26	<.0001
Range (AU)	23-315	11-95
Bone marrow data
Not available	19 (37%)	4 (25%)
Normal marrow	25 (49%)	5 (31%)
Decreased myelopoiesis	2 (4%)	1 (6%)
Increased myelopoiesis	2 (4%)	2 (13%)
Possible dysplasia	2 (4%)	2 (13%)
Lymphocytosis	1 (2%)	1 (6%)
FcγR genotype^-153
FcγRIIA-131R	0.59	0.61
FcγRIIA-131H	0.41	0.39	NS
FcγRIIIB-NA1	0.29	0.32
FcγRIIIB-NA2	0.71	0.68	NS

*NS, not significant.

F0-151

ANC, absolute neutrophil count.

F0-152

Mean ± SD.

F0-153

Genotype frequencies in a control (Dutch) population are 0.47 and 0.53 for FcγRIIA-131R and -131H,respectively and 0.37 and 0.63 for FcγRIIIB-NA1and -NA2, respectively.2

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