Table 2.

Definition of T- and B-Cell Immune Functions Assessment Criteria

T-cell function  
 T+: T cell counts >1,000/μL  
  and Responses to mitogens (PHA): positive (≥50,000 cpm)  
  and Responses to antigen (tetanus toxoid): positive (>15,000 cpm) 
 T−: Responses to mitogens: negative or low (<50,000 cpm) 
  and Responses to antigens: negative (<5,000 cpm)  
 T low: Any other combination  
B-cell function  
 B+: Positive antibody responses at least to two immunization antigens* in the absence of Ig substitution  
 B−: Absence of antibody responses after immunization  
  and IgA: ≤0.1 g/L  
 B low: Any other combination 
T-cell function  
 T+: T cell counts >1,000/μL  
  and Responses to mitogens (PHA): positive (≥50,000 cpm)  
  and Responses to antigen (tetanus toxoid): positive (>15,000 cpm) 
 T−: Responses to mitogens: negative or low (<50,000 cpm) 
  and Responses to antigens: negative (<5,000 cpm)  
 T low: Any other combination  
B-cell function  
 B+: Positive antibody responses at least to two immunization antigens* in the absence of Ig substitution  
 B−: Absence of antibody responses after immunization  
  and IgA: ≤0.1 g/L  
 B low: Any other combination 

*Two antigens among polio viruses, tetanus, and diphtheria toxoids.

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