Definition of T- and B-Cell Immune Functions Assessment Criteria
T-cell function |
T+: T cell counts >1,000/μL |
and Responses to mitogens (PHA): positive (≥50,000 cpm) |
and Responses to antigen (tetanus toxoid): positive (>15,000 cpm) |
T−: Responses to mitogens: negative or low (<50,000 cpm) |
and Responses to antigens: negative (<5,000 cpm) |
T low: Any other combination |
B-cell function |
B+: Positive antibody responses at least to two immunization antigens* in the absence of Ig substitution |
B−: Absence of antibody responses after immunization |
and IgA: ≤0.1 g/L |
B low: Any other combination |
T-cell function |
T+: T cell counts >1,000/μL |
and Responses to mitogens (PHA): positive (≥50,000 cpm) |
and Responses to antigen (tetanus toxoid): positive (>15,000 cpm) |
T−: Responses to mitogens: negative or low (<50,000 cpm) |
and Responses to antigens: negative (<5,000 cpm) |
T low: Any other combination |
B-cell function |
B+: Positive antibody responses at least to two immunization antigens* in the absence of Ig substitution |
B−: Absence of antibody responses after immunization |
and IgA: ≤0.1 g/L |
B low: Any other combination |
*Two antigens among polio viruses, tetanus, and diphtheria toxoids.