LOH Analysis in Paired Germline and Leukemic DNAs
| Markers . | Location . | Bat . | Big . | Bul . | Dia . | Imb . | Jun . | Lec . | Mal . | Pot . | Van . | Ber . | Bouq . | Gob . | Mel . | Ver . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D11S932 | p15 | □ | □ | □ | NA | NA | □ | NA | H | NA | □ | NA | H | H | H | NA |
| D11S913 | q12 | ▪ | □ | □ | NA | NA | □ | NA | NA | NA | H | NA | H | H | H | NA |
| D11S901 | q13.5 | ▪ | ▪ | NA | NA | NA | H | NA | NA | NA | ▪ | NA | □ | □ | □ | NA |
| D11S917 | q14.3 | ▪ | ▪ | □ | NA | NA | ▪ | NA | ▪ | NA | H | NA | □ | □ | H | NA |
| D11S1817 | q22-23 | ▪ | ▪ | NA | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | □ | H | □ | □ | □ |
| D11S1819 | q22-23 | ▪ | ▪ | H | ▪ | ▪ | ▪ | ▪ | H | ▪ | ▪ | □ | □ | □ | □ | □ |
| D11S2179-150 | q23 | ▪ | H | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | H | ▪ | H | H | □ | □ | H |
| D11S1778 | q23 | ▪ | H | ▪ | H | ▪ | ▪ | ▪ | ▪ | H | ▪ | □ | □ | □ | □ | □ |
| D11S1294 | q23 | NA | H | ▪ | ▪ | NA | ▪ | NA | ▪ | H | H | □ | □ | □ | □ | NA |
| D11S2180 | q23 | H | ▪ | ▪ | H | ▪ | ▪ | H | ▪ | NA | H | □ | NA | □ | H | □ |
| D11S2178 | q23 | ▪ | ▪ | NA | □ | ▪ | ▪ | ▪ | ▪ | ▪ | H | □ | □ | □ | □ | H |
| D11S1300 | q23 | ▪ | H | H | □ | ▪ | ▪ | H | ▪ | H | H | □ | NA | □ | □ | H |
| D11S1391 | q23 | ▪ | ▪ | H | □ | H | H | ▪ | ▪ | ▪ | ▪ | □ | □ | H | □ | □ |
| D11S938 | q23 | NA | H | □ | NA | NA | ▪ | NA | NA | NA | ▪ | NA | □ | □ | H | NA |
| D11S925 | q23 | ▪ | NA | □ | NA | NA | ▪ | NA | NA | NA | ▪ | NA | □ | □ | □ | NA |
| D11S934 | q23.3 | H | H | □ | NA | NA | H | NA | ▪ | NA | NA | NA | □ | □ | NA | NA |
| D11S910 | q25 | NA | H | H | NA | NA | □ | NA | NA | NA | NA | NA | NA | NA | □ | NA |
| Markers . | Location . | Bat . | Big . | Bul . | Dia . | Imb . | Jun . | Lec . | Mal . | Pot . | Van . | Ber . | Bouq . | Gob . | Mel . | Ver . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D11S932 | p15 | □ | □ | □ | NA | NA | □ | NA | H | NA | □ | NA | H | H | H | NA |
| D11S913 | q12 | ▪ | □ | □ | NA | NA | □ | NA | NA | NA | H | NA | H | H | H | NA |
| D11S901 | q13.5 | ▪ | ▪ | NA | NA | NA | H | NA | NA | NA | ▪ | NA | □ | □ | □ | NA |
| D11S917 | q14.3 | ▪ | ▪ | □ | NA | NA | ▪ | NA | ▪ | NA | H | NA | □ | □ | H | NA |
| D11S1817 | q22-23 | ▪ | ▪ | NA | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | □ | H | □ | □ | □ |
| D11S1819 | q22-23 | ▪ | ▪ | H | ▪ | ▪ | ▪ | ▪ | H | ▪ | ▪ | □ | □ | □ | □ | □ |
| D11S2179-150 | q23 | ▪ | H | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | H | ▪ | H | H | □ | □ | H |
| D11S1778 | q23 | ▪ | H | ▪ | H | ▪ | ▪ | ▪ | ▪ | H | ▪ | □ | □ | □ | □ | □ |
| D11S1294 | q23 | NA | H | ▪ | ▪ | NA | ▪ | NA | ▪ | H | H | □ | □ | □ | □ | NA |
| D11S2180 | q23 | H | ▪ | ▪ | H | ▪ | ▪ | H | ▪ | NA | H | □ | NA | □ | H | □ |
| D11S2178 | q23 | ▪ | ▪ | NA | □ | ▪ | ▪ | ▪ | ▪ | ▪ | H | □ | □ | □ | □ | H |
| D11S1300 | q23 | ▪ | H | H | □ | ▪ | ▪ | H | ▪ | H | H | □ | NA | □ | □ | H |
| D11S1391 | q23 | ▪ | ▪ | H | □ | H | H | ▪ | ▪ | ▪ | ▪ | □ | □ | H | □ | □ |
| D11S938 | q23 | NA | H | □ | NA | NA | ▪ | NA | NA | NA | ▪ | NA | □ | □ | H | NA |
| D11S925 | q23 | ▪ | NA | □ | NA | NA | ▪ | NA | NA | NA | ▪ | NA | □ | □ | □ | NA |
| D11S934 | q23.3 | H | H | □ | NA | NA | H | NA | ▪ | NA | NA | NA | □ | □ | NA | NA |
| D11S910 | q25 | NA | H | H | NA | NA | □ | NA | NA | NA | NA | NA | NA | NA | □ | NA |
Symbols: ▪, LOH; □, no LOH.
Abbreviations: H, germinal homozygosity; NA, no data available.
Marker located within the ATM gene.