Table 1. Summary of Sex, Weight, E coli... | American Society of Hematology

Table 1.

Summary of Sex, Weight, E coli Dose, DEGR VIIa Dose, and Survival of the DEGR VIIa-Treated and Control Groups

Experiment No.	Sex	Weight (kg)	E coliStock (CFU × 10¹⁰/mL)	E coli at T + 120′ (CFU × 10⁶/ mL blood)	VIIa₁ (280 μg/kg) × 5	Survival (h)
Treated
VIIa₁ 1	Female	5.9	1.59	3.85	Yes	43
VIIa₁ 2	Female	3.6	1.65	0.09	Yes	119
VIIa₁ 3	Female	4.1	1.54	22.60	Yes	168
VIIa₁ 6	Male	4.2	1.52	13.00	Yes	168
VIIa₁ 8	Female	5.4	8.40	27.00	Yes	31
VIIa₁ 9	Male	5.7	1.30	6.05	Yes	65
VIIa₁ 10	Male	5.7	1.44	29.00	Yes	168
VIIa₁ 12	Male	6.6	1.36	2.32	Yes	168
Average SE		5.2 ± 0.4	2.35 ± 0.86	12.98 ± 4.13		116 ± 22^*
Control
4	Female	4.3	1.66	13.90	No	86
5	Female	5.2	1.50	27.10	No	15
7	Male	6.4	7.25	4.32	No	26
13	Female	4.8	1.37	16.4	No	26
14	Female	7.5	1.36	10.8	No	24
15	Male	14.8	1.46	9.90	No	14
16	Female	11.7	8.23	2.43	No	15
17	Female	7.3	5.03	12.1	No	14
Average SE		7.7 ± 1.9	3.48 ± 1.21	12.11 ± 4.82		26 ± 8

Experiment No.	Sex	Weight (kg)	E coliStock (CFU × 10¹⁰/mL)	E coli at T + 120′ (CFU × 10⁶/ mL blood)	VIIa₁ (280 μg/kg) × 5	Survival (h)
Treated
VIIa₁ 1	Female	5.9	1.59	3.85	Yes	43
VIIa₁ 2	Female	3.6	1.65	0.09	Yes	119
VIIa₁ 3	Female	4.1	1.54	22.60	Yes	168
VIIa₁ 6	Male	4.2	1.52	13.00	Yes	168
VIIa₁ 8	Female	5.4	8.40	27.00	Yes	31
VIIa₁ 9	Male	5.7	1.30	6.05	Yes	65
VIIa₁ 10	Male	5.7	1.44	29.00	Yes	168
VIIa₁ 12	Male	6.6	1.36	2.32	Yes	168
Average SE		5.2 ± 0.4	2.35 ± 0.86	12.98 ± 4.13		116 ± 22^*
Control
4	Female	4.3	1.66	13.90	No	86
5	Female	5.2	1.50	27.10	No	15
7	Male	6.4	7.25	4.32	No	26
13	Female	4.8	1.37	16.4	No	26
14	Female	7.5	1.36	10.8	No	24
15	Male	14.8	1.46	9.90	No	14
16	Female	11.7	8.23	2.43	No	15
17	Female	7.3	5.03	12.1	No	14
Average SE		7.7 ± 1.9	3.48 ± 1.21	12.11 ± 4.82		26 ± 8

*Denotes that value of the treated group differs significantly from that of the control group, (P value = .0008).