IL-6 and IL-8 Concentrations at T = 8 Hours of the DEGR VIIa-Treated and Control Groups
| Experiment No. . | IL-6 (ng/mL) . | IL-8 (ng/mL) . |
|---|---|---|
| Treated | ||
| VIIa1 1 | 65 | 44 |
| VIIa1 2 | 62 | 26 |
| VIIa1 3 | 69 | 33 |
| VIIa1 6 | 106 | 35 |
| VIIa1 8 | 89 | 15 |
| VIIa1 9 | 134 | 38 |
| VIIa1 10 | 44 | 20 |
| VIIa1 12 | 82 | 15 |
| Average SE | 81 ± 103-150 | 28 ± 3.93-150 |
| Control | ||
| 4 | 723 | 31 |
| 5 | 1,336 | 64 |
| 7 | 1,244 | 69 |
| 13 | 285 | 24 |
| 14 | 936 | 53 |
| 15 | 2,413 | 93 |
| 16 | 1,200 | 78 |
| 17 | 1,908 | 69 |
| Average SE | 1,256 ± 236 | 60 ± 8.2 |
| Experiment No. . | IL-6 (ng/mL) . | IL-8 (ng/mL) . |
|---|---|---|
| Treated | ||
| VIIa1 1 | 65 | 44 |
| VIIa1 2 | 62 | 26 |
| VIIa1 3 | 69 | 33 |
| VIIa1 6 | 106 | 35 |
| VIIa1 8 | 89 | 15 |
| VIIa1 9 | 134 | 38 |
| VIIa1 10 | 44 | 20 |
| VIIa1 12 | 82 | 15 |
| Average SE | 81 ± 103-150 | 28 ± 3.93-150 |
| Control | ||
| 4 | 723 | 31 |
| 5 | 1,336 | 64 |
| 7 | 1,244 | 69 |
| 13 | 285 | 24 |
| 14 | 936 | 53 |
| 15 | 2,413 | 93 |
| 16 | 1,200 | 78 |
| 17 | 1,908 | 69 |
| Average SE | 1,256 ± 236 | 60 ± 8.2 |
The concentration of IL-6 at T = 4 hours was 187 ± 30 ng/mL and 383 ± 144 ng/mL for the treated and control groups, respectively. The concentration of IL-8 at T = 4 hours was 51 ± 6 ng/mL and 60 ± 15 ng/mL for the treated and control groups, respectively. The limit of detection for IL-6 and IL-8 was 2.5 and 0.2 ng/mL, respectively.
Denotes that those values of the treated group differ significantly from those of the control group. The P values for IL-6– and IL-8–treated versus control groups were P = .0001 andP = .0074, respectively.