Table 1.

Effect of Anti-CD20 Antibodies on the Cell Cycle of Ramos Cells

Experiment No. Antibody Exposure % of Cells in G1 % of Cells in S + G2/M
1  Control (64.1)  32.9  67.1  
 B1  35.3 64.6  
 1F5  35.5  64.5  
2  Control (64.1) 21.6  78.4  
 B1  24.6  75.4  
 1F5  29.9 70.1  
3  Control (64.1)  20.6  79.5  
 1F5 23.5  76.5  
4  Control  30.2  69.8 
 (64.1 + GAM)  
 1F5 + GAM  43.0  57.0 
Experiment No. Antibody Exposure % of Cells in G1 % of Cells in S + G2/M
1  Control (64.1)  32.9  67.1  
 B1  35.3 64.6  
 1F5  35.5  64.5  
2  Control (64.1) 21.6  78.4  
 B1  24.6  75.4  
 1F5  29.9 70.1  
3  Control (64.1)  20.6  79.5  
 1F5 23.5  76.5  
4  Control  30.2  69.8 
 (64.1 + GAM)  
 1F5 + GAM  43.0  57.0 

Analysis of cell cycle distribution by propidium iodide staining and flow cytometry as described in Materials and Methods.

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